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扁平苔藓:发病机制的综述与更新

Lichen planus: review and update on pathogenesis.

作者信息

Scully C, el-Kom M

出版信息

J Oral Pathol. 1985 Jul;14(6):431-58. doi: 10.1111/j.1600-0714.1985.tb00516.x.

DOI:10.1111/j.1600-0714.1985.tb00516.x
PMID:3926971
Abstract

Lichen planus (LP) is a common oral disorder which may represent the manifestation of a mucosal reaction to a variety of aetiological factors. Of the many immunological changes described in LP several may be epiphenomena although a cell-mediated immune response to unidentified antigens or antigenic changes clearly is involved. Associations with drugs or systemic disorders are well-defined in some patients but may, in others, be aleatoric. Finally, the prognosis of oral LP not only differs from that of cutaneous LP but there is little doubt that in a few instances LP is a premalignant condition.

摘要

扁平苔藓(LP)是一种常见的口腔疾病,可能代表黏膜对多种病因因素产生反应的表现。在LP中描述的众多免疫变化中,有些可能是附带现象,尽管对未明抗原或抗原性变化的细胞介导免疫反应显然是存在的。在一些患者中,与药物或全身性疾病的关联已明确,但在另一些患者中可能是偶然的。最后,口腔LP的预后不仅与皮肤LP不同,而且毫无疑问,在少数情况下,LP是一种癌前状态。

相似文献

1
Lichen planus: review and update on pathogenesis.扁平苔藓:发病机制的综述与更新
J Oral Pathol. 1985 Jul;14(6):431-58. doi: 10.1111/j.1600-0714.1985.tb00516.x.
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