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扁平苔藓:发病机制理论

Lichen planus: a theory of pathogenesis.

作者信息

Lacy M F, Reade P C, Hay K D

出版信息

Oral Surg Oral Med Oral Pathol. 1983 Nov;56(5):521-6. doi: 10.1016/0030-4220(83)90100-7.

DOI:10.1016/0030-4220(83)90100-7
PMID:6580596
Abstract

From a continuing study of 108 cases of oral mucosal lichen planus, including so-called drug-induced lichenoid reactions, the response of patients to topical therapy and to drugs implicated in inducing the lichenoid reactions was used to construct a hypothetical model regarding the pathogenesis of the condition. The results were interpreted to indicate that lichen planus is a predetermined condition or diathesis, perhaps genetically based, rather than a simple cause-and-effect disorder.

摘要

通过对108例口腔黏膜扁平苔藓病例(包括所谓的药物性苔藓样反应)的持续研究,利用患者对局部治疗以及对引发苔藓样反应的药物的反应,构建了一个关于该病发病机制的假设模型。研究结果表明,扁平苔藓是一种预先确定的状况或素质,可能基于遗传,而非简单的因果性疾病。

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Lichen planus: a theory of pathogenesis.扁平苔藓:发病机制理论
Oral Surg Oral Med Oral Pathol. 1983 Nov;56(5):521-6. doi: 10.1016/0030-4220(83)90100-7.
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