口腔鳞状细胞癌患者的全身免疫炎症和预后免疫营养指数。
Systemic immune-inflammation and prognostic immune nutritional index in oral squamous cell carcinoma patients.
机构信息
Department of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Department of Ultrasound, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
出版信息
Biomark Med. 2024;18(17-18):759-770. doi: 10.1080/17520363.2024.2394390. Epub 2024 Sep 13.
To investigate the systemic immune-inflammation index and prognostic immune nutritional index in the prognostic evaluation of oral squamous cell carcinoma. We analyzed retrospectively the relationship between systemic immune-inflammation index, prognostic immune nutritional index and clinicopathological variables and the overall survival of 262 patients who underwent radical surgery. Multivariate analysis showed high systemic immune-inflammation index (Hazard ratio = 3.062, 95% CI: 1.021-8.251), low prognostic immune nutritional index (Hazard ratio = 0.297, 95% CI: 0.139-0.636), tumor node metastasis classification 3-4 (Hazard ratio = 9.862, 95% CI: 4.658-20.880) patients have worse overall survival. Preoperative systemic immune-inflammation index and prognostic immune nutritional index are independent risk factors for prognostic survival status in oral squamous cell carcinoma.
探讨全身免疫炎症指数和预后免疫营养指数在口腔鳞状细胞癌预后评估中的作用。我们回顾性分析了 262 例接受根治性手术的患者的全身免疫炎症指数、预后免疫营养指数与临床病理变量及总生存时间的关系。多因素分析显示，全身免疫炎症指数高（危险比=3.062，95%CI：1.021-8.251）、预后免疫营养指数低（危险比=0.297，95%CI：0.139-0.636）、肿瘤淋巴结转移分期 3-4 期（危险比=9.862，95%CI：4.658-20.880）的患者总生存时间更差。术前全身免疫炎症指数和预后免疫营养指数是口腔鳞状细胞癌预后生存状态的独立危险因素。
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