Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan.
Sci Rep. 2022 Aug 30;12(1):14787. doi: 10.1038/s41598-022-19177-6.
Oral dysfunction and dysphagia after oral cancer treatment are linked to altered nutritional status. We aimed to identify specific oral functions related to nutritional status. We conducted a cross-sectional study from September 2019 to December 2021, recruited 75 participants (median age: 72.0 years), including 52 males and 23 females, collected background data, and evaluated oral function. The Mini Nutritional Assessment-Short Form (MNA-SF) scores were divided into three groups (normal nutritional status, at risk of malnutrition, and malnourished), and a multi-group comparison was conducted for each oral function measurement (microorganisms, oral dryness, occlusal force, tongue pressure, masticatory function, and Eating Assessment Tool [EAT-10]). The primary tumor site was the tongue in 31 patients (41.3%), gingiva in 30 (40.0%), and others in 14 (18.7%). Multiple comparisons revealed significant differences in occlusal force, tongue pressure, masticatory function, and EAT-10 levels, categorized as Type I (Transport type) and Type III (Occlusion type) postoperative oral dysfunctions, between each MNA-SF group. Multiple regression analysis showed a statistically significant association with MNA-SF in terms of masticatory function and EAT-10 levels, categorized as Type I. Type I and Type III are risk factors for malnutrition, confirming that different types of postoperative oral dysfunction require unique nutritional guidance.
口腔癌治疗后口腔功能障碍和吞咽困难与营养状况改变有关。我们旨在确定与营养状况相关的特定口腔功能。我们进行了一项横断面研究，时间为 2019 年 9 月至 2021 年 12 月，共招募了 75 名参与者（中位年龄：72.0 岁），包括 52 名男性和 23 名女性，收集背景数据并评估口腔功能。微型营养评估-短表（MNA-SF）评分分为三组（营养正常、有营养不良风险和营养不良），对每个口腔功能测量（微生物、口腔干燥、咬合力、舌压、咀嚼功能和饮食评估工具 [EAT-10]）进行多组比较。31 例（41.3%）原发性肿瘤位于舌，30 例（40.0%）位于牙龈，14 例（18.7%）位于其他部位。多重比较显示，在咬合力、舌压、咀嚼功能和 EAT-10 水平方面，每个 MNA-SF 组之间存在显著差异，分为 I 型（转运型）和 III 型（闭锁型）术后口腔功能障碍。多元回归分析显示，咀嚼功能和 EAT-10 水平与 MNA-SF 有统计学显著关联，分为 I 型。I 型和 III 型是营养不良的危险因素，这证实了不同类型的术后口腔功能障碍需要独特的营养指导。
