Muratani H, Kawasaki T, Ueno M, Kawazoe N, Fujishima M
Life Sci. 1985 Aug 19;37(7):645-9. doi: 10.1016/0024-3205(85)90431-x.
In order to determine whether the usual feeding pattern actually modifies the circadian rhythms of urinary excretion of water and electrolytes, we compared the circadian rhythm characteristics in patients receiving total parenteral nutrition (TPN group) with those in patients on an ordinary hospital diet (control group). Statistically significant circadian rhythms were detected in all of the urinary variables investigated herein by using the population mean-cosinor method in both groups. In addition, there were no statistically significant differences of the mesor, the %-amplitude and the acrophase between the two groups. These results suggest that the usual feeding pattern is not a main determinant in forming the circadian rhythm characteristics of human urinary variables.
为了确定通常的进食模式是否真的会改变水和电解质的昼夜尿排泄节律，我们比较了接受全胃肠外营养的患者（TPN组）与食用普通医院饮食的患者（对照组）的昼夜节律特征。在两组中，通过使用总体均值-余弦分析法，在所研究的所有尿液变量中均检测到具有统计学意义的昼夜节律。此外，两组之间的中值、振幅百分比和峰相位没有统计学上的显著差异。这些结果表明，通常的进食模式不是形成人类尿液变量昼夜节律特征的主要决定因素。
