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意大利中毒家养及野生动物体内违禁除草剂4,6-二硝基邻甲酚(DNOC)的测定

The Determination of the Prohibited Herbicide 4,6-Dinitro-Ortho-Cresol (DNOC) in Poisoned Domestic and Wild Animals in Italy.

作者信息

Rocchi Rachele, Tinelli Antonella, Gatti Giuseppe, Badagliacca Pietro, Cocco Antonio, Cantelmi Maria Chiara, Damiano Antonella, Scortichini Giampiero, Merola Carmine, Petrini Antonio

机构信息

Istituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100 Teramo, Italy.

Department of Veterinary Medicine, University of Bari "Aldo Moro", Valenzano, 70010 Bari, Italy.

出版信息

Animals (Basel). 2024 Aug 26;14(17):2483. doi: 10.3390/ani14172483.

DOI:10.3390/ani14172483
PMID:39272268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11394050/
Abstract

This study reports the determination of DNOC in the baits and gastric contents of poisoned dogs and wild canids collected in the Abruzzo region between 2014 and 2022. A total of 663 samples of the baits and carcasses of domestic and wild animals were analyzed for the determination of DNOC through GC-MS. DNOC was found to be present in 58 cases from 663 analyzed samples, with 49 poison baits and nine gastric content samples from dogs and red foxes. This study confirms for the first time that the banned pesticide DNOC still poisons both domestic and wild animals in the Abruzzo region. It should be considered that this study was carried out on a population of animals from a regional geographical area, and more detailed country-wide studies need to be carried out to obtain the incidence of poisoning from this herbicide in Italy. Furthermore, these findings emphasize the importance of considering this chemical in differential diagnosis during toxicological investigations of animal poisoning.

摘要

本研究报告了2014年至2022年期间在阿布鲁佐地区收集的中毒犬类和野生犬科动物的诱饵及胃内容物中DNOC的测定情况。通过气相色谱 - 质谱联用仪(GC-MS)对总共663份家养和野生动物的诱饵及尸体样本进行了分析,以测定DNOC。在663份分析样本中的58例中发现了DNOC,其中有49份毒饵以及9份来自犬类和赤狐的胃内容物样本。本研究首次证实,被禁用的农药DNOC仍在毒害阿布鲁佐地区的家养和野生动物。应当考虑到,本研究是针对一个地区地理区域内的动物群体进行的,需要开展更详细的全国性研究,以获取该除草剂在意大利造成中毒的发生率。此外,这些发现强调了在动物中毒毒理学调查的鉴别诊断中考虑这种化学物质的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36b/11394050/64346aa337e9/animals-14-02483-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36b/11394050/b6bd9d85c3c3/animals-14-02483-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36b/11394050/64346aa337e9/animals-14-02483-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36b/11394050/b6bd9d85c3c3/animals-14-02483-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f36b/11394050/64346aa337e9/animals-14-02483-g002.jpg

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Foods. 2022 Jul 1;11(13):1963. doi: 10.3390/foods11131963.
2
Dinitroaniline herbicide pendimethalin affects development and induces biochemical and histological alterations in zebrafish early-life stages.二硝基苯胺类除草剂二甲戊灵对斑马鱼早期发育的影响及其致毒的生化和组织学机理
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Use of poisoned baits against wildlife. A retrospective 17-year study in the natural environment of Extremadura (Spain).
使用毒饵防治野生动物。在埃斯特雷马杜拉(西班牙)的自然环境中进行的一项回顾性 17 年研究。
Environ Pollut. 2022 Jun 15;303:119098. doi: 10.1016/j.envpol.2022.119098. Epub 2022 Mar 3.
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Retrospective data analysis of animal poisoning events in Liguria.利古里亚动物中毒事件的回顾性数据分析。
Vet Anim Sci. 2021 May 23;13:100178. doi: 10.1016/j.vas.2021.100178. eCollection 2021 Sep.
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Epidemiological Study of Pesticide Poisoning in Domestic Animals and Wildlife in Portugal: 2014-2020.葡萄牙家畜和野生动物农药中毒的流行病学研究:2014 - 2020年
Front Vet Sci. 2021 Jan 14;7:616293. doi: 10.3389/fvets.2020.616293. eCollection 2020.
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Local context and environment as risk factors for acute poisoning in animals in northwest Italy.意大利西北部地区的局部环境和地域因素与动物急性中毒的关系。
Sci Total Environ. 2020 Mar 20;709:136016. doi: 10.1016/j.scitotenv.2019.136016. Epub 2019 Dec 20.
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Types of pesticides involved in domestic and wild animal poisoning in Italy.意大利涉及家养和野生动物中毒的农药类型。
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Long-term Data from the Swedish National Environmental Monitoring Program of Pesticides in Surface Waters.瑞典国家地表水环境中农药监测计划的长期数据。
J Environ Qual. 2019 Jul;48(4):1109-1119. doi: 10.2134/jeq2019.02.0056.
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Vet J. 2018 May;235:63-69. doi: 10.1016/j.tvjl.2018.04.003. Epub 2018 Apr 6.