Königswieser H
Prog Pediatr Surg. 1985;18:173-81.
Ten groups of authors investigated their cases of splenectomized children in four different indication groups for frequency of postsplenectomy infection. Only severe infections were included and defined. A total of 1039 splenectomized patients were evaluated for the rate of infection and lethality following splenectomy. It was seen that in all groups there was a definite rate of infection and resultant deaths which was lowest in traumatic splenectomies and highest in malignant hematological diseases. The frequency of infection was highest in the early postoperative phase. Infections, however, still occurred more than 6 years after splenectomy. In older children the vulnerability to infection was less than in younger ones, but the mortality in older children was higher. The gravity of this danger can be seen, and effective therapeutic measures must be found and carried out. Especially, the attitude towards splenectomies should be changed in favor of spleen-preserving surgical procedures.
十组作者对四个不同适应证组的脾切除儿童病例进行了研究，以探讨脾切除术后感染的发生率。仅纳入并定义了严重感染。总共对1039例脾切除患者进行了脾切除术后感染率和致死率的评估。结果发现，所有组中都存在一定的感染率和由此导致的死亡，其中创伤性脾切除术后的感染率最低，恶性血液疾病患者的感染率最高。感染频率在术后早期最高。然而，脾切除术后6年以上仍有感染发生。年龄较大的儿童对感染的易感性低于年龄较小的儿童，但年龄较大儿童的死亡率更高。这种危险的严重性可见一斑，必须找到并实施有效的治疗措施。特别是，应改变对脾切除术的态度，转而支持保留脾脏的手术方法。
