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一种具有独特时间反转算法的、可实现可控声场的柔性超声换能器。

A Unique Time-Reversal Algorithm-Enabled Flexible Ultrasound Transducer with a Controllable Acoustic Field.

作者信息

Jia Lu, Yan Yingzhan, Xu Jing, Gao Yuan

机构信息

Information Science Academy, China Electronics Technology Group Corporation, Beijing 100142, China.

National Key Laboratory of Integrated Circuits and Microsystems, Beijing 100142, China.

出版信息

Sensors (Basel). 2024 Aug 30;24(17):5635. doi: 10.3390/s24175635.

DOI:10.3390/s24175635
PMID:39275546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11398051/
Abstract

Flexible ultrasonic devices represent a feasible technology for providing timely signal detection and even a non-invasive disease treatment for the human brain. However, the deformation of the devices is always accompanied by a change in the acoustic field, making it hard for accurate focusing. Herein, we report a stable and flexible transducer. This device can generate a high-intensity acoustic signal with a controllable acoustic field even when the device is bent. The key is to use a low-impedance piezoelectric material and an island-bridge device structure, as well as to design a unique time-reversal algorithm to correct the deviation of signals after transcranial propagation. To provide an in-depth study of the acoustic field of flexible devices, we also analyze the effects of mechanical deformation and structural parameters on the corresponding acoustic response.

摘要

柔性超声设备是一种可行的技术,可用于及时进行信号检测,甚至对人脑进行非侵入性疾病治疗。然而,设备的变形总是伴随着声场的变化,这使得精确聚焦变得困难。在此,我们报告一种稳定且柔性的换能器。即使该设备弯曲时,此装置也能产生具有可控声场的高强度声信号。关键在于使用低阻抗压电材料和岛桥式器件结构,以及设计独特的时间反转算法来校正经颅传播后信号的偏差。为了深入研究柔性设备的声场,我们还分析了机械变形和结构参数对相应声学响应的影响。

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A Unique Time-Reversal Algorithm-Enabled Flexible Ultrasound Transducer with a Controllable Acoustic Field.一种具有独特时间反转算法的、可实现可控声场的柔性超声换能器。
Sensors (Basel). 2024 Aug 30;24(17):5635. doi: 10.3390/s24175635.
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本文引用的文献

1
Transcranial volumetric imaging using a conformal ultrasound patch.使用共形超声贴片的经颅容积成像。
Nature. 2024 May;629(8013):810-818. doi: 10.1038/s41586-024-07381-5. Epub 2024 May 22.
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Flexible and Stretchable Electrochemical Sensors for Biological Monitoring.用于生物监测的柔性可拉伸电化学传感器
Adv Mater. 2023 Aug 28:e2305917. doi: 10.1002/adma.202305917.
3
Wearable Optical Fiber Sensors in Medical Monitoring Applications: A Review.可穿戴光纤传感器在医疗监测应用中的研究进展综述
Sensors (Basel). 2023 Jul 25;23(15):6671. doi: 10.3390/s23156671.
4
BBB opening with focused ultrasound in nonhuman primates and Parkinson's disease patients: Targeted AAV vector delivery and PET imaging.在非人灵长类动物和帕金森病患者中使用聚焦超声打开 BBB:靶向 AAV 载体传递和 PET 成像。
Sci Adv. 2023 Apr 21;9(16):eadf4888. doi: 10.1126/sciadv.adf4888. Epub 2023 Apr 19.
5
Bioadhesive ultrasound for long-term continuous imaging of diverse organs.生物黏附超声用于多种器官的长期连续成像。
Science. 2022 Jul 29;377(6605):517-523. doi: 10.1126/science.abo2542. Epub 2022 Jul 28.
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Ultrasonic Methods for Brain Imaging: Techniques and Implications.用于脑成像的超声方法:技术与影响
IEEE Trans Biomed Eng. 2022 Nov;69(11):3526-3537. doi: 10.1109/TBME.2022.3173035. Epub 2022 Oct 19.
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Flexible Doppler ultrasound device for the monitoring of blood flow velocity.用于监测血流速度的柔性多普勒超声设备。
Sci Adv. 2021 Oct 29;7(44):eabi9283. doi: 10.1126/sciadv.abi9283. Epub 2021 Oct 27.
8
A flexible, stretchable system for simultaneous acoustic energy transfer and communication.一种用于同时进行声能传输和通信的柔性、可拉伸系统。
Sci Adv. 2021 Oct;7(40):eabg2507. doi: 10.1126/sciadv.abg2507. Epub 2021 Sep 29.
9
Continuous monitoring of deep-tissue haemodynamics with stretchable ultrasonic phased arrays.采用可拉伸超声相控阵对深部组织血流动力学进行连续监测。
Nat Biomed Eng. 2021 Jul;5(7):749-758. doi: 10.1038/s41551-021-00763-4. Epub 2021 Jul 16.
10
Flexible Ultrasonic Patch for Accelerating Chronic Wound Healing.用于加速慢性伤口愈合的柔性超声贴片。
Adv Healthc Mater. 2021 Oct;10(19):e2100785. doi: 10.1002/adhm.202100785. Epub 2021 Jul 1.