Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Makihata Engineering, San Jose, CA 95130, USA.
Science. 2022 Jul 29;377(6605):517-523. doi: 10.1126/science.abo2542. Epub 2022 Jul 28.
Continuous imaging of internal organs over days could provide crucial information about health and diseases and enable insights into developmental biology. We report a bioadhesive ultrasound (BAUS) device that consists of a thin and rigid ultrasound probe robustly adhered to the skin via a couplant made of a soft, tough, antidehydrating, and bioadhesive hydrogel-elastomer hybrid. The BAUS device provides 48 hours of continuous imaging of diverse internal organs, including blood vessels, muscle, heart, gastrointestinal tract, diaphragm, and lung. The BAUS device could enable diagnostic and monitoring tools for various diseases.
连续数日对内脏器官进行成像，可以提供有关健康和疾病的关键信息，并深入了解发育生物学。我们报告了一种生物粘附超声（BAUS）设备，该设备由一个薄而刚性的超声探头组成，通过由柔软、坚韧、防脱水和生物粘附水凝胶-弹性体混合制成的偶联剂牢固地粘附在皮肤上。BAUS 设备可提供 48 小时的连续成像，可用于多种内部器官，包括血管、肌肉、心脏、胃肠道、横膈膜和肺。BAUS 设备可以为各种疾病提供诊断和监测工具。
