Maruyama N, Kumagai Y, Ishida Y, Sato H, Sugano I, Nagao K, Kondo Y
Virchows Arch A Pathol Anat Histopathol. 1985;407(2):159-65. doi: 10.1007/BF00737073.
An epithelioid haemangioendothelioma arising in a 43-year-old Japanese woman is presented. The patient first complained of severe back pain and neurogenic disturbances due to compression fracture of the spinal bone. Radiographically the tumour masses showed osteolytic lesions without reactive new bone formation. Similar lesions were noted in other bones. Biopsy and surgical specimens showed the features of epithelioid haemangioendothelioma. A lymphocyte associated antigen, HLA-DR which has been regarded as a B lymphocyte marker was detected in the tumour cells. The importance of this finding was emphasized with respect to the identification or classification of vascular tumours.
本文报告了一例发生于一名43岁日本女性的上皮样血管内皮瘤。患者最初因脊椎骨压缩性骨折而主诉严重背痛和神经功能障碍。影像学检查显示肿瘤肿块为溶骨性病变，无反应性新骨形成。其他骨骼也发现了类似病变。活检和手术标本显示为上皮样血管内皮瘤的特征。在肿瘤细胞中检测到一种与淋巴细胞相关的抗原HLA - DR，它一直被视为B淋巴细胞标志物。就血管肿瘤的识别或分类而言，强调了这一发现的重要性。
