Ansell J, Bhawan J, Cohen S, Sullivan J, Sherman D
Cancer. 1982 Oct 15;50(8):1506-12. doi: 10.1002/1097-0142(19821015)50:8<1506::aid-cncr2820500810>3.0.co;2-3.
The case history of a patient with diffuse histiocytic lymphoma and skin lesions characteristic of malignant angioendotheliomatosis is reported. The patient initially responded to aggressive chemotherapy but quickly had a relapse, CNS disease developed, and the patient died one year after diagnosis. Microscopic, ultrastructural, and surface membrane studies showed that the intravascular tumor cells were not of endothelial origin. The morphologic similarity of the malignant intravascular cells and peripheral blood cells, as well as the demonstration of surface membrane immunoglobulin on malignant blood cells suggested that, in some cases, unusual features of malignant lymphoma may be confused with malignant angioendotheliomatosis.
报告了一例弥漫性组织细胞淋巴瘤患者，其皮肤病变具有恶性血管内皮瘤病的特征。该患者最初对积极化疗有反应，但很快复发，出现中枢神经系统疾病，诊断后一年死亡。显微镜、超微结构和表面膜研究表明，血管内肿瘤细胞并非内皮起源。恶性血管内细胞与外周血细胞在形态学上的相似性，以及恶性血细胞表面膜免疫球蛋白的显示表明，在某些情况下，恶性淋巴瘤的不寻常特征可能与恶性血管内皮瘤病相混淆。
