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冠状面畸形角度比值是否会影响青少年特发性脊柱侧凸的支具治疗效果?

Does the coronal deformity angular ratio affect bracing outcome in adolescent idiopathic scoliosis?

机构信息

Rigshospitalet, Spine Unit, Department of Orthopedic Surgery, Copenhagen, Denmark.

Scottish Rite for Children, Dallas, TX, USA.

出版信息

Eur Spine J. 2024 Oct;33(10):3760-3766. doi: 10.1007/s00586-024-08486-1. Epub 2024 Sep 14.

Abstract

PURPOSE

To examine if coronal deformity angular ratio (C-DAR) serves as a predictor for progression to surgical magnitude in patients with Adolescent Idiopathic Scoliosis (AIS) treated with thoracolumbar sacral orthosis (TLSO).

METHODS

Patients with AIS, prescribed a full-time TLSO, Cobb angle 20-40°, Risser 0-2, who wore the brace ≥ 12.9 h and reached skeletal maturity/surgery were included retrospectively. C-DAR was defined as the Cobb angle divided by the number of vertebrae in the curve, yielding a larger value in short curves. The association between C-DAR and the risk of progression to surgical magnitude (> 45°) was assessed. Secondly, we evaluated the association between pre-treatment Cobb angle and in-brace correction on the risk of progression to > 45°.

RESULTS

We included 165 patients with a mean Cobb angle of 30 ± 6°. Of these, 46/165 (28%) progressed ≥ 6° and 26/165 (16%) reached surgical magnitude at the end of treatment. C-DAR was a significant predictor for risk of progression to surgical magnitude with an OR of 1.9 (CI 1.2-2.9) per unit increase in C-DAR. A threshold value of 5.15 was established and demonstrated an OR 5.9 (CI 2.1-17.9) for curve progression to a surgical magnitude. Likewise, pre-treatment Cobb angle showed a significant OR 1.3(CI 1.2-1.4) per degree increase in Cobb, whereas in-brace % correction showed OR 0.96 (CI 0.93-0.98).

CONCLUSION

C-DAR is an independent predictor for progression to a surgical magnitude in AIS patients treated with bracing. Patients with a higher C-DAR should be counseled to help set realistic expectations regarding the likelihood of curve progression despite compliance with brace wear.

摘要

目的

探讨冠状面畸形角度比(C-DAR)是否可作为青少年特发性脊柱侧凸(AIS)患者接受胸腰骶支具(TLSO)治疗后进展至手术程度的预测指标。

方法

回顾性纳入 AIS 患者,支具处方为全天佩戴 TLSO,Cobb 角 20-40°,Risser 征 0-2,支具佩戴时间≥12.9 小时,且达到骨骼成熟/手术年龄。C-DAR 定义为 Cobb 角除以曲线中的椎体数,短曲线的比值更大。评估 C-DAR 与进展至手术程度(>45°)的风险之间的相关性。其次,我们评估了治疗前 Cobb 角与支具内矫正对进展至>45°的风险之间的相关性。

结果

共纳入 165 例患者,平均 Cobb 角为 30±6°。其中,46/165(28%)进展≥6°,26/165(16%)在治疗结束时达到手术程度。C-DAR 是进展至手术程度的风险的显著预测因子,C-DAR 每增加一个单位,比值比(OR)为 1.9(95%CI 1.2-2.9)。建立了 5.15 的阈值,表明 C-DAR 增加 5.9(95%CI 2.1-17.9)时,曲线进展至手术程度的比值比为 5.9。同样,治疗前 Cobb 角每增加 1°,OR 为 1.3(95%CI 1.2-1.4),而支具内矫正率的 OR 为 0.96(95%CI 0.93-0.98)。

结论

C-DAR 是 AIS 患者接受支具治疗后进展至手术程度的独立预测因子。C-DAR 较高的患者应接受咨询,以帮助其设定切合实际的期望,了解即使遵守支具佩戴,曲线仍可能进展。

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