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梅尼埃病中的前庭旁小管:一项组织病理学研究

Paravestibular canaliculus in Meniere's disease. A histopathological study.

作者信息

Ikeda M, Sando I

出版信息

Ann Otol Rhinol Laryngol Suppl. 1985 Jul-Aug;118:11-6. doi: 10.1177/00034894850940s403.

DOI:10.1177/00034894850940s403
PMID:3927811
Abstract

The paravestibular canaliculus (PVC) and its contents were studied in 27 temporal bones from individuals with Meniere's disease and in the same number of controls. The specimens were examined by the medial view graphic reconstruction method and/or histologically under a light microscope. In most of these bones (88.9% of controls and 85.2% of Meniere's bones) only one PVC was noted; in the remaining bones (11.1% of controls and 14.8% of Meniere's bones) two PVCs were recognized. Most of the PVCs (88.9%) in both control and Meniere's bones were located in the petrous bone anterolateral to the vestibular aqueduct (VA). In one third of both control and Meniere's bones the PVC extended below the inferior margin of the posterior semicircular canal. In 74.1% of the Meniere's bones the PVCs were noted to exit directly to the posterior cranial fossa, whereas such a course was present in only 40.7% of controls. The difference in this parameter between control and Meniere's disease bones is statically significant and appears to be related to the size of the VA. The length of the PVC, however, seems to be independent of both the size of the VA and the degree of development (thickness) of the petrous bones surrounding the PVC. In four Meniere's bones a part of the main vein in the PVC was absent; this was never observed in a control bone. We found no other evidence in this study to link the function or anatomy of the PVC to Meniere's disease.

摘要

对27例梅尼埃病患者的颞骨以及相同数量的对照者颞骨中的前庭旁小管(PVC)及其内容物进行了研究。通过内侧视图图形重建法和/或在光学显微镜下进行组织学检查这些标本。在大多数这些颞骨中(对照组的88.9%和梅尼埃病患者颞骨的85.2%)仅发现一条PVC;在其余的颞骨中(对照组的11.1%和梅尼埃病患者颞骨的14.8%)发现两条PVC。对照组和梅尼埃病患者颞骨中的大多数PVC(88.9%)位于前庭导水管(VA)前外侧的岩骨内。对照组和梅尼埃病患者颞骨中有三分之一的PVC延伸至后半规管下缘以下。在74.1%的梅尼埃病患者颞骨中,PVC直接通向颅后窝,而对照组中只有40.7%有这样的走行。对照组和梅尼埃病患者颞骨在这个参数上的差异具有统计学意义,并且似乎与VA的大小有关。然而,PVC的长度似乎与VA的大小以及PVC周围岩骨的发育程度(厚度)均无关。在4例梅尼埃病患者的颞骨中,PVC内的主要静脉有一部分缺失;在对照颞骨中从未观察到这种情况。在本研究中,我们没有发现其他证据将PVC的功能或解剖结构与梅尼埃病联系起来。

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Paravestibular canaliculus in Meniere's disease. A histopathological study.梅尼埃病中的前庭旁小管:一项组织病理学研究
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