Department of Endocrinology, Hulunbeir People's Hospital, Hulunbuir, China.
Hulunbuir Zhong Meng Hospital, Hulunbuir, China.
Endokrynol Pol. 2024;75(4):395-402. doi: 10.5603/ep.99842.
Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. As a new detection method for DPN, corneal confocal microscopy (CCM) is characterised by rapid, non-invasive, sensitive, and quantitative characteristics, as well as good repeatability. By detecting changes in the corneal nerves, DPN can be diagnosed early, and the severity of neuropathy evaluated. It is currently an ideal DPN evaluation method and has good clinical application prospects. This paper reviews the application and progress of CCM in the evaluation of DPN and summarises the evaluation methods of CCM, corneal nerve, and DPN to provide new ideas for the clinical diagnosis and treatment of DPN.
糖尿病周围神经病变（DPN）是糖尿病最常见的慢性并发症之一。角膜共焦显微镜（CCM）作为 DPN 的一种新的检测方法，具有快速、无创、敏感、定量及重复性好等特点，通过检测角膜神经的变化，可早期诊断 DPN，并评估神经病变的严重程度，是目前较为理想的 DPN 评价方法，具有良好的临床应用前景。本文就 CCM 在 DPN 中的评估应用及进展作一综述，总结 CCM、角膜神经及 DPN 的评估方法，为 DPN 的临床诊断和治疗提供新思路。
