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双能X线吸收法在亚临床心血管疾病预测中的重要作用。

The essential role of dual-energy x-ray absorptiometry in the prediction of subclinical cardiovascular disease.

作者信息

Yang Sisi, Chen Qin, Fan Yang, Zhang Cuntai, Cao Ming

机构信息

Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Front Cardiovasc Med. 2024 Aug 29;11:1377299. doi: 10.3389/fcvm.2024.1377299. eCollection 2024.

Abstract

Subclinical cardiovascular disease (Sub-CVD) is an early stage of cardiovascular disease and is often asymptomatic. Risk factors, including hypertension, diabetes, obesity, and lifestyle, significantly affect Sub-CVD. Progress in imaging technology has facilitated the timely identification of disease phenotypes and risk categorization. The critical function of dual-energy x-ray absorptiometry (DXA) in predicting Sub-CVD was the subject of this research. Initially used to evaluate bone mineral density, DXA has now evolved into an indispensable tool for assessing body composition, which is a pivotal determinant in estimating cardiovascular risk. DXA offers precise measurements of body fat, lean muscle mass, bone density, and abdominal aortic calcification, rendering it an essential tool for Sub-CVD evaluation. This study examined the efficacy of DXA in integrating various risk factors into a comprehensive assessment and how the application of machine learning could enhance the early discovery and control of cardiovascular risks. DXA exhibits distinct advantages and constraints compared to alternative imaging modalities such as ultrasound, computed tomography, magnetic resonance imaging, and positron emission tomography. This review advocates DXA incorporation into cardiovascular health assessments, emphasizing its crucial role in the early identification and management of Sub-CVD.

摘要

亚临床心血管疾病(Sub-CVD)是心血管疾病的早期阶段,通常无症状。包括高血压、糖尿病、肥胖和生活方式在内的风险因素会显著影响亚临床心血管疾病。成像技术的进步有助于及时识别疾病表型和风险分类。双能X线吸收法(DXA)在预测亚临床心血管疾病中的关键作用是本研究的主题。DXA最初用于评估骨密度,现在已发展成为评估身体成分的不可或缺的工具,而身体成分是估计心血管风险的关键决定因素。DXA可精确测量体脂、瘦肌肉质量、骨密度和腹主动脉钙化,使其成为亚临床心血管疾病评估的重要工具。本研究考察了DXA在将各种风险因素整合为综合评估方面的功效,以及机器学习的应用如何能够加强心血管风险的早期发现和控制。与超声、计算机断层扫描、磁共振成像和正电子发射断层扫描等其他成像方式相比,DXA具有明显的优势和局限性。本综述主张将DXA纳入心血管健康评估,强调其在亚临床心血管疾病的早期识别和管理中的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/545c/11393745/5e3bf000e294/fcvm-11-1377299-g001.jpg

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