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甲型流感感染作为巨细胞动脉炎的潜在触发因素:一例报告。

Influenza A infection as a potential trigger of giant cell arteritis: A case report.

作者信息

Kosteska Misajlevska Dragana, Pavol Peter, Ziaka Mairi

机构信息

Center for Geriatric Medicine & Rehabilitation, Clinic for Geriatric Medicine, Bruderholz Hospital, Bruderholz, Switzerland.

Department of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.

出版信息

SAGE Open Med Case Rep. 2024 Sep 14;12:2050313X241272666. doi: 10.1177/2050313X241272666. eCollection 2024.

DOI:10.1177/2050313X241272666
PMID:39280335
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11401139/
Abstract

Presenting as a large vessel vasculitis, giant cell arteritis (GCA) manifests with various symptoms, including fever, myalgias, headache, and jaw claudication. Although the precise pathogenesis of GCA remains incompletely elucidated, there is speculation about the involvement of environmental factors and infectious agents like bacteria and viruses in its development. Nevertheless, data on the potential link between influenza infection and GCA are limited. In this report, we present the case of an 88-year-old patient diagnosed with GCA following a severe influenza A infection.

摘要

巨细胞动脉炎(GCA)表现为大血管血管炎,有多种症状,包括发热、肌痛、头痛和颌部间歇性运动障碍。尽管GCA的确切发病机制仍未完全阐明,但有人推测环境因素以及细菌和病毒等感染因子在其发病过程中发挥了作用。然而,关于流感感染与GCA之间潜在联系的数据有限。在本报告中,我们介绍了一名88岁患者的病例,该患者在严重甲型流感感染后被诊断为GCA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2f1/11401139/869145121737/10.1177_2050313X241272666-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2f1/11401139/018e6a353002/10.1177_2050313X241272666-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2f1/11401139/869145121737/10.1177_2050313X241272666-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2f1/11401139/018e6a353002/10.1177_2050313X241272666-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2f1/11401139/869145121737/10.1177_2050313X241272666-fig2.jpg

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本文引用的文献

1
Giant Cell Arteritis: Advances in Understanding Pathogenesis and Implications for Clinical Practice.巨细胞动脉炎:发病机制研究进展及其对临床实践的意义。
Cells. 2024 Jan 31;13(3):267. doi: 10.3390/cells13030267.
2
Increased incidence of giant cell arteritis and associated stroke during the COVID-19 pandemic in Spain: A nation-wide population study.在西班牙 COVID-19 大流行期间巨细胞动脉炎和相关卒中发病率增加:一项全国范围内的人群研究。
Autoimmun Rev. 2023 Jun;22(6):103341. doi: 10.1016/j.autrev.2023.103341. Epub 2023 Apr 14.
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Giant cell arteritis or polymyalgia rheumatica after influenza vaccination: A study of 12 patients and a literature review.
接种流感疫苗后发生巨细胞动脉炎或风湿性多肌痛:12 例患者的研究及文献复习。
Autoimmun Rev. 2021 Feb;20(2):102732. doi: 10.1016/j.autrev.2020.102732. Epub 2020 Dec 14.
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Aortic involvement in giant cell arteritis.巨细胞动脉炎中的主动脉受累情况。
Joint Bone Spine. 2021 Mar;88(2):105045. doi: 10.1016/j.jbspin.2020.06.018. Epub 2020 Jul 7.
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Infections Are Associated With Increased Risk of Giant Cell Arteritis: A Population-based Case-control Study from Southern Sweden.感染与巨细胞动脉炎风险增加相关:来自瑞典南部的基于人群的病例对照研究。
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Does low risk of infections as a marker of effective immunity predict increased risk of subsequent giant cell arteritis or polymyalgia rheumatica? A Danish population-based case-control study.感染风险低作为有效免疫的标志是否预示着随后发生巨细胞动脉炎或风湿性多肌痛的风险增加?一项基于丹麦人群的病例对照研究。
Clin Epidemiol. 2018 Oct 16;10:1533-1543. doi: 10.2147/CLEP.S158293. eCollection 2018.
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Vasculitis related to viral and other microbial agents.与病毒及其他微生物因子相关的血管炎
Best Pract Res Clin Rheumatol. 2015 Apr;29(2):226-43. doi: 10.1016/j.berh.2015.05.007. Epub 2015 Jun 11.
9
Incidence of giant cell arteritis and characteristics of patients: data-driven analysis of comorbidities.巨细胞动脉炎的发病率和患者特征:基于共病数据驱动的分析。
Arthritis Care Res (Hoboken). 2015 Mar;67(3):390-5. doi: 10.1002/acr.22429.
10
Clinical practice. Giant-cell arteritis and polymyalgia rheumatica.临床实践。巨细胞动脉炎和风湿性多肌痛。
N Engl J Med. 2014 Jul 3;371(1):50-7. doi: 10.1056/NEJMcp1214825.