Taylor R J, Bond C M
Br Med J (Clin Res Ed). 1985 Aug 24;291(6494):518-20. doi: 10.1136/bmj.291.6494.518.
During the first month after the limited National Health Service drug list came into effect 17 cooperative general practitioners recorded the actions taken when a now prohibited drug would formerly have been prescribed. An average of 6% of direct surgery contacts with patients and 8% of indirect contacts with patients were affected by the new regulations, but in 2% and 4% of cases respectively the patient received the same pharmacological substance under a different (generic or approved) name. Where a real change in pharmacological constitution or formulation had been required four fifths of these substitutes were considered by the doctors to result in less effective treatment. In 1% of contacts no drug was issued or recommended where one would formerly have been given.
在国家医疗服务体系有限药品清单生效后的第一个月,17名合作全科医生记录了在过去会开具现已被禁止药物时所采取的行动。与患者的直接诊疗接触中平均有6%、间接接触中有8%受到新规定影响,但分别有2%和4%的病例中,患者以不同(通用名或获批名)名称接受了相同的药理物质。在需要真正改变药理成分或剂型的情况下,医生认为这些替代药物中有五分之四会导致治疗效果降低。在1%的诊疗接触中,原本会给药或推荐用药的情况未再进行。