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39周引产的初产妇剖宫产率与传统管理的比较:一项开放标签随机分配研究。

Caesarean Section frequency in Nulliparous Women induced at 39 weeks versus conventional management: An open label random allocation study.

作者信息

Majid Erum, Zuberi Bader Faiyaz, Gul Kanwal, Jam Hira, Haseena Gul

机构信息

Erum Majid, FCPS Associate Professor Department of Obstetrics/Gynaecology, Jinnah Postgraduate Medical Center (JPMC), Karachi, Pakistan.

Bader Faiyaz Zuberi, FCPS Meritorious Professor, OMI Hospital, Karachi, Pakistan.

出版信息

Pak J Med Sci. 2024 Sep;40(8):1690-1694. doi: 10.12669/pjms.40.8.9099.

DOI:10.12669/pjms.40.8.9099
PMID:39281249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11395340/
Abstract

OBJECTIVE

To compare frequency of caesarean section in singleton primary-para women induced at 39 week and its comparison with conventional management. The other objective was comparison of perinatal and neonatal outcomes.

METHOD

Open random allocation study was conducted at Gynae/Obst Department JPMC during period from 1 June 2022 to 30 September 2023. Primiparous women with singleton pregnancy without risk factors with gestational age 38 weeks 0 days to 38 weeks six days attending the anti-natal clinic offered to participate after consent. Non-probability convenience sampling method was used for induction. Randomization was done using random number table into one of the two groups, Group-A in which induction was done at 39 weeks while in Group-B induction was done conventionally. Mean age ±SD, gestational age and delivery time was calculated and compared by Student's t test. Frequency of CS, perinatal and neonatal outcomes was compared by χ test.

RESULTS

Eighty-two women were inducted in Group-A and eighty-five in Group-B. The mean delivery time in Group-A was significantly more at 8.12±2.77 hours while in Group-B was 7.0±2.62 hours ( = .005). Frequency of CS between two groups was not statistically significant, it was 5 (6.1%) in Group-A and 2 (2.4%) in Group-B ( = 0.412). No significant difference in frequency of NICU admission was seen, in Group-A 8.54% babies were admitted to NICU while in Group-B 16.47% were admitted to NICU ( = 0.122).

CONCLUSION

No significant difference was observed in frequencies of CS, Foetal, Neonatal, and Maternal outcomes.

摘要

目的

比较单胎初产妇在39周引产时剖宫产的发生率,并与传统管理方法进行比较。另一个目的是比较围产期和新生儿结局。

方法

于2022年6月1日至2023年9月30日期间在卡拉奇真纳医学院妇产科进行开放性随机分配研究。孕龄为38周0天至38周6天、无危险因素的单胎初产妇在同意后被邀请参加产前检查。采用非概率方便抽样方法进行引产。使用随机数字表将其随机分为两组,A组在39周时引产,而B组采用传统引产方法。计算平均年龄±标准差、孕龄和分娩时间,并通过学生t检验进行比较。通过χ检验比较剖宫产的发生率、围产期和新生儿结局。

结果

A组有82名妇女引产,B组有85名。A组的平均分娩时间明显更长,为8.12±2.77小时,而B组为7.0±2.62小时(P = 0.005)。两组之间剖宫产的发生率无统计学意义,A组为5例(6.1%),B组为2例(2.4%)(P = 0.412)。新生儿重症监护病房(NICU)收治率无显著差异,A组8.54%的婴儿入住NICU,而B组为16.47%(P = 0.122)。

结论

在剖宫产率、胎儿、新生儿和产妇结局方面未观察到显著差异。

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Caesarean Section frequency in Nulliparous Women induced at 39 weeks versus conventional management: An open label random allocation study.39周引产的初产妇剖宫产率与传统管理的比较:一项开放标签随机分配研究。
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本文引用的文献

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Rates of Induction of Labor at 39 Weeks and Cesarean Delivery Following Publication of the ARRIVE Trial.《ARRIVE试验》发表后39周引产率及剖宫产率
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Reducing pelvic floor injury by induction of labor.通过引产减少盆底损伤。
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Changes in obstetrical practices and pregnancy outcomes following the ARRIVE trial.ARRIVE试验后产科实践和妊娠结局的变化。
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The ARRIVE Trial: Towards a universal recommendation of induction of labour at 39 weeks?ARRIVE 试验:是否朝着 39 周引产的通用推荐迈进?
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Elective Induction of Labor in the 39th Week of Gestation Compared With Expectant Management of Low-Risk Multiparous Women.39 孕周选择性引产与低危经产妇期待管理的比较。
Obstet Gynecol. 2019 Aug;134(2):282-287. doi: 10.1097/AOG.0000000000003371.
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Induction of labour indications and timing: A systematic analysis of clinical guidelines.引产指征和时机:临床指南的系统分析。
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