Alıravcı Isıl Deniz, Ertekin Yusuf Haydar, Can Gamze, Alkan Sevil
Işıl Deniz Alıravcı, MD Assistant Professor, Department of Infectious Diseases and Clinical Microbiology, Canakkale Onsekiz Mart University, Canakkale, Türkiye.
Yusuf Haydar Ertekin, MD Associate Professor, Department of Family Medicine, Canakkale Onsekiz Mart University, Canakkale, Türkiye.
Pak J Med Sci. 2024 Sep;40(8):1702-1708. doi: 10.12669/pjms.40.8.8455.
Given the limited studies on types of vaccination and infection rates among health care workers (HCWs) in Türkiye, we analyzed the demographic, clinical, and vaccination characteristics as well as the attitudes of HCWs who have been infected with COVID-19.
We retrospectively analyzed demographic and clinical data on breakthrough COVID-19 infections in HCWs from hospital surveillance data collected between April 5, 2020, and November 1, 2022. The comparison was based on four subgroups that consisted of unvaccinated, one-shot-vaccinated, homologous vaccinated, and heterologous vaccinated individuals. Participants who received various combinations of Sinovac/CoronaVac and/or BioNTech/Pfizer vaccines were compared for detection of COVID-19.
During a 33-month period of 744 HCWs who contracted COVID-19, women (65.3%) and nurses (28.9%) were the most affected, followed by doctors (25.8%). Of the infected HCWs, only 1.3% required hospitalization, 0.3% required ICU support, and 98.4% were outpatients. By vaccination status, 143 of the HCWs (19.2%) were unvaccinated, 292 (39.2%) were homologously vaccinated, 294 (39.5%) were heterologously vaccinated, 15 (2%) received a single shot, 206 (27.7%) received two shots, and 165 (22.2%) received three shots. All HCWs contracted COVID-19 at a mean of 134-days (range:1-539) after vaccination. While the proportions of homologously and heterologously vaccinated HCWs were similar, the time elapsed from vaccination to contracting COVID-19 varied (mean 143.4±106.7 vs.126.4±82.43 days).
Among both outpatients and inpatients with COVID-19, women HCWs outnumbered men HCWs. HCWs who received homologous vaccination contracted COVID-19 later than those who received heterologous vaccination.
鉴于土耳其针对医护人员疫苗接种类型和感染率的研究有限，我们分析了感染新型冠状病毒肺炎（COVID-19）的医护人员的人口统计学、临床和疫苗接种特征以及他们的态度。
我们回顾性分析了2020年4月5日至2022年11月1日期间从医院监测数据中获取的医护人员COVID-19突破性感染的人口统计学和临床数据。比较基于四个亚组，分别为未接种疫苗、接种一剂疫苗、同源接种和异源接种的个体。对接受了科兴/克尔来福和/或辉瑞/BioNTech疫苗不同组合的参与者进行COVID-19检测比较。
在33个月期间，744名感染COVID-19的医护人员中，女性（65.3%）和护士（28.9%）受影响最大，其次是医生（25.8%）。在感染的医护人员中，只有1.3%需要住院治疗，0.3%需要重症监护病房（ICU）支持，98.4%为门诊患者。按疫苗接种状况划分，143名医护人员（19.2%）未接种疫苗，292名（39.2%）为同源接种，294名（39.5%）为异源接种，15名（2%）接种了一剂，206名（27.7%）接种了两剂，165名（22.2%）接种了三剂。所有医护人员在接种疫苗后平均134天（范围：1 - 539天）感染COVID-19。虽然同源接种和异源接种的医护人员比例相似，但从接种疫苗到感染COVID-19的时间有所不同（平均143.4±106.7天对126.4±82.43天）。
在COVID-19门诊和住院患者中，女性医护人员数量多于男性医护人员。接受同源接种的医护人员比接受异源接种的医护人员感染COVID-19的时间更晚。
