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新型研究:1%镁银合金对牛源细菌种类的抗菌及生物相容性作用

Novel Study Antimicrobial and Biocompatibility Effect of Magnesium Silver Alloys 1% on Bovine Bacterial Species.

作者信息

Nomier Yousra, Meiβner Jessica, Kietzmann Manfred

机构信息

Department of Pharmacology and Toxicology, Pharmacy College, Jazan University, Jazan, Saudi Arabia.

Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Foundation, Hannover, Germany.

出版信息

Vet Med Int. 2023 Mar 27;2023:8627515. doi: 10.1155/2023/8627515. eCollection 2023.

DOI:10.1155/2023/8627515
PMID:39281289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11401738/
Abstract

MgAg 1% alloys inhibit bacterial growth during the dry-off period. MgAg1% silver and magnesium amount was determined and the supernatant was used for the detection of antibacterial tests against and and var. . The antibacterial effect of AgNO solution and degradation medium of MgAg1% sticks were evaluated. The bouillon dilution test showed a 5-fold reduction in bacterial colonies. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) calculations were used to test the antibacterial activity. The Brilliant Black Reduction Test (BRT-MRL screening test) showed inhibition of bacteria at AgNO concentrations 0.01 mmol/l and 3 ml of degradation medium. Results were satisfying, concerning biocompatibility, degradation, and antibacterial effects.

摘要

1%的MgAg合金在干燥期可抑制细菌生长。测定了MgAg1%中银和镁的含量,并将上清液用于针对[具体细菌名称1]、[具体细菌名称2]和[具体细菌名称3]变种的抗菌测试检测。评估了AgNO溶液和1%MgAg棒降解介质的抗菌效果。肉汤稀释试验表明细菌菌落减少了5倍。采用最低抑菌浓度(MIC)和最低杀菌浓度(MBC)计算来测试抗菌活性。灿烂黑还原试验(BRT - MRL筛选试验)表明,在AgNO浓度为0.01 mmol/l和3 ml降解介质时,[具体细菌名称4]细菌受到抑制。在生物相容性、降解和抗菌效果方面,结果令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/c7080f42cd1e/VMI2023-8627515.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/acc89d39b31b/VMI2023-8627515.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/53deee1d8429/VMI2023-8627515.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/fab3cb1e2743/VMI2023-8627515.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/c7080f42cd1e/VMI2023-8627515.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/acc89d39b31b/VMI2023-8627515.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/53deee1d8429/VMI2023-8627515.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/fab3cb1e2743/VMI2023-8627515.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/c7080f42cd1e/VMI2023-8627515.006.jpg

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本文引用的文献

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Antimicrobial Properties on Non-Antibiotic Drugs in the Era of Increased Bacterial Resistance.细菌耐药性增加时代非抗生素药物的抗菌特性
Antibiotics (Basel). 2020 Mar 2;9(3):107. doi: 10.3390/antibiotics9030107.
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Influence of the Microstructure and Silver Content on Degradation, Cytocompatibility, and Antibacterial Properties of Magnesium-Silver Alloys In Vitro.微观结构和银含量对镁银合金体外降解、细胞相容性及抗菌性能的影响
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Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli.银离子对金黄色葡萄球菌和大肠杆菌的抗菌活性及作用机制
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