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新型研究:1%镁银合金对牛源细菌种类的抗菌及生物相容性作用

Novel Study Antimicrobial and Biocompatibility Effect of Magnesium Silver Alloys 1% on Bovine Bacterial Species.

作者信息

Nomier Yousra, Meiβner Jessica, Kietzmann Manfred

机构信息

Department of Pharmacology and Toxicology, Pharmacy College, Jazan University, Jazan, Saudi Arabia.

Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Foundation, Hannover, Germany.

出版信息

Vet Med Int. 2023 Mar 27;2023:8627515. doi: 10.1155/2023/8627515. eCollection 2023.

Abstract

MgAg 1% alloys inhibit bacterial growth during the dry-off period. MgAg1% silver and magnesium amount was determined and the supernatant was used for the detection of antibacterial tests against and and var. . The antibacterial effect of AgNO solution and degradation medium of MgAg1% sticks were evaluated. The bouillon dilution test showed a 5-fold reduction in bacterial colonies. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) calculations were used to test the antibacterial activity. The Brilliant Black Reduction Test (BRT-MRL screening test) showed inhibition of bacteria at AgNO concentrations 0.01 mmol/l and 3 ml of degradation medium. Results were satisfying, concerning biocompatibility, degradation, and antibacterial effects.

摘要

1%的MgAg合金在干燥期可抑制细菌生长。测定了MgAg1%中银和镁的含量,并将上清液用于针对[具体细菌名称1]、[具体细菌名称2]和[具体细菌名称3]变种的抗菌测试检测。评估了AgNO溶液和1%MgAg棒降解介质的抗菌效果。肉汤稀释试验表明细菌菌落减少了5倍。采用最低抑菌浓度(MIC)和最低杀菌浓度(MBC)计算来测试抗菌活性。灿烂黑还原试验(BRT - MRL筛选试验)表明,在AgNO浓度为0.01 mmol/l和3 ml降解介质时,[具体细菌名称4]细菌受到抑制。在生物相容性、降解和抗菌效果方面,结果令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3c6/11401738/acc89d39b31b/VMI2023-8627515.001.jpg

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