Jia Yunlong, Tian Wenjie, Li Yuyao, Teng Yuyan, Liu Xiaolin, Li Zhengyu, Zhao Mingsheng
Institute of Immunology and Molecular Medicine, Jining Medical University, Jining, China.
Heliyon. 2024 Aug 28;10(17):e37098. doi: 10.1016/j.heliyon.2024.e37098. eCollection 2024 Sep 15.
The COVID-19 outbreak has garnered significant global attention due to its impact on human health. Despite its relatively low fatality rate, the virus affects multiple organ systems, resulting in various symptoms such as palpitations, headaches, muscle pain, and hearing loss among COVID-19 patients and those recovering from the disease. These symptoms impose a substantial physical, psychological, and social burden on affected individuals. On February 15, 2020, the Chinese government advised incorporating antimalarial drugs into the guidelines issued by the National Health Commission of China for preventing, diagnosing, and treating COVID-19 pneumonia. We examine the adverse effects of Chloroquine (CQ) in treating COVID-19 complications to understand why it is no longer the primary treatment for the disease.
新型冠状病毒肺炎(COVID-19)疫情因其对人类健康的影响而受到全球广泛关注。尽管该病毒致死率相对较低,但它会影响多个器官系统,导致COVID-19患者及康复者出现心悸、头痛、肌肉疼痛和听力损失等各种症状。这些症状给受影响个体带来了巨大的身体、心理和社会负担。2020年2月15日,中国政府建议将抗疟药物纳入中国国家卫生健康委员会发布的COVID-19肺炎预防、诊断和治疗指南。我们研究了氯喹(CQ)治疗COVID-19并发症的不良反应,以了解它为何不再是该疾病的主要治疗药物。