Zhao Guimei, Chang Jinchun, Wei Kaipeng
Medical Laboratory Teaching and Research Office, School of Health, Quanzhou Medical College, 362011, Quanzhou, Fujian Province, China.
Heliyon. 2024 Aug 28;10(17):e37027. doi: 10.1016/j.heliyon.2024.e37027. eCollection 2024 Sep 15.
Breast cancer (BC), the most common malignant tumor in women worldwide, has been increasing in incidence and mortality year by year. While significant progress has been made in understanding the pathogenesis of breast cancer, certain aspects remain under investigation. Human papillomavirus (HPV) is known to be closely associated with a variety of cancers, including cervical, vulvar, anal, and head and neck cancers. It is important to note that while HPV is associated with the mentioned cancers, its direct association with breast cancer remains a topic of debate and research. In this paper, we review the research progress on the correlation between breast cancer and HPV infection, and put forward the problems in the current research. This review aims to shed light on the current understanding and controversies surrounding the correlation between HPV infection and breast cancer, providing insights for future research aimed at enhancing prevention and treatment strategies.
乳腺癌（BC）是全球女性中最常见的恶性肿瘤，其发病率和死亡率逐年上升。尽管在了解乳腺癌发病机制方面取得了重大进展，但某些方面仍在研究中。人乳头瘤病毒（HPV）已知与多种癌症密切相关，包括宫颈癌、外阴癌、肛门癌和头颈癌。需要注意的是，虽然HPV与上述癌症有关，但其与乳腺癌的直接关联仍是一个有争议的研究话题。在本文中，我们综述了乳腺癌与HPV感染相关性的研究进展，并提出了当前研究中存在的问题。本综述旨在阐明目前对HPV感染与乳腺癌相关性的理解和争议，为未来旨在加强预防和治疗策略的研究提供见解。
