Antimicrobial Susceptibility Patterns of Species and Molecular Detection of Isolated from Patients with Urinary Tract Infection in a Tertiary Care Hospital in Bangladesh.

One of the most prevalent infectious diseases identified in both communities and hospitalized patients is urinary tract infection (UTI). is evolved into a clinically pertinent uropathogen due to its evolving resistance to multiple antimicrobial agentsThis study, detects antimicrobial susceptibility patterns of species and molecular detection of from patients with urinary tract infections. In this cross-sectional observational study, 165 urine samples were obtained from clinically diagnosed patients with UTIs of different ages and gender. species were identified by standard microbiological procedure and PCR (by using species-specific primers for ). A modified Kirby Bauer Disc diffusion method was used to identify the antimicrobial susceptibility pattern following Clinical and Laboratory Standards Institute (CLSI) guidelines. Out of 165 urine samples, 134 samples yielded positive cultures. species were isolated from 23 (17.1%) urine samples. Among all , 16 (69.6%) isolates were . , detected by PCR assay. A higher (30.4%) proportion of -positive patients were from the age group 48-57 years and female patients (78.2%) had a higher prevalence. Enterococcal infection was found in 56.5% of non-catheterized patients and 43.5% of catheterized patients. Vancomycin and linezolid (78.3%) and meropenem (73.9%) sensitivity was prevalent among all species. They showed 100% resistance towards ceftriaxone, cefixime 95.7%, cefuroxime 91.3%, azithromycin 82.6%. This research indicated the occurrence of species and the advent of multidrug-resistant in patients with UTIs. Routine speciation and antimicrobial susceptibility testing of in various clinical samples is encouraged.