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停用番泻叶泻药后结肠黑变病的结肠镜下消退情况

Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use.

作者信息

Chiba Toshimi, Wang Ting, Kikuchi Satoshi

机构信息

Division of Internal Medicine, Department of Oral Medicine, Iwate Medical University, Morioka, Iwate, Japan.

Department of Gastroenterology, Sanai Hospital, Morioka, Iwate, Japan.

出版信息

Int Med Case Rep J. 2024 Sep 11;17:783-787. doi: 10.2147/IMCRJ.S475869. eCollection 2024.

DOI:10.2147/IMCRJ.S475869
PMID:39282237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11402352/
Abstract

Melanosis coli occurs with the administration of stimulant laxatives for the relief of constipation. However, the duration of macroscopic improvement of melanosis coli after discontinuation of anthracene laxatives is not well understood. We describe the case of an 81-year-old female diagnosed with melanosis coli via colonoscopy who had been taking senna laxatives for 5 years. Seven months after cessation of senna laxatives, colonoscopy showed no melanosis coli in the colon. This impressive report describes the observation of melanosis coli with colonoscopy; 7 months after the withdrawal of senna stimulant laxatives, melanosis coli resolved.

摘要

结肠黑变病与使用刺激性泻药缓解便秘有关。然而,停用蒽醌类泻药后结肠黑变病宏观改善的持续时间尚不清楚。我们描述了一例81岁女性病例,通过结肠镜检查诊断为结肠黑变病,该患者服用番泻叶泻药5年。停用番泻叶泻药7个月后,结肠镜检查显示结肠无结肠黑变病。这份令人印象深刻的报告描述了通过结肠镜检查对结肠黑变病的观察;停用番泻叶刺激性泻药7个月后,结肠黑变病消失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4177/11402352/0006e00278de/IMCRJ-17-783-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4177/11402352/1f771ab1241a/IMCRJ-17-783-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4177/11402352/fc9222eedcf0/IMCRJ-17-783-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4177/11402352/0006e00278de/IMCRJ-17-783-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4177/11402352/1f771ab1241a/IMCRJ-17-783-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4177/11402352/fc9222eedcf0/IMCRJ-17-783-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4177/11402352/0006e00278de/IMCRJ-17-783-g0003.jpg

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Colorectal neoplasms in melanosis coli: a survey in Japan and a worldwide meta-analysis.结直肠肿瘤合并结肠黑变病:日本的调查和全球的荟萃分析。
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Melanosis Coli.结肠黑变病
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Efficacy, long-term safety, and impact on quality of life of elobixibat in more severe constipation: Post hoc analyses of two phase 3 trials in Japan.
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Adenoma Detection is Increased in the Setting of Melanosis Coli.在结肠黑变病的情况下腺瘤检出率增加。
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