Department of Nursing, New York School of Career and Applied Studies, Touro University, 3 Times Square, 3rd Floor, Room 322, New York, NY, 10044, USA.
Department of Nursing, New York School of Career and Applied Studies, Touro University, 3 Times Square, 3rd Floor, Room 320, New York, NY, 10044, USA.
Adv Exp Med Biol. 2024;1457:185-197. doi: 10.1007/978-3-031-61939-7_10.
SARS-CoV-2 is a virus in the coronavirus family originating out of Wuhan, China clinically known as COVID-19. While traditionally thought of as a respiratory virus, COVID-19 can have a multi-organ impact due to its invasion and widespread distribution throughout the body and via the angiotensin converting enzyme. Neurologic events due to COVID-19 are common, especially in the critically ill, and are called Neuro-COVID. Among these events are peripheral and central nervous system diseases such as Guillain-Barré, ischemic stroke, and various types of encephalitis. The impact of Neuro-COVID is devastating and is often far more severe than its non-COVID-19 form. Immunosuppressive or immunomodulatory therapy is often a mainstay of treatment, such as for encephalitis and Guillain-Barré, respectively, while management may fall in line with conventional processes in most cases, such as ischemic stroke. Much remains to be studied about the evaluation and management of Neuro-COVID.
SARS-CoV-2 是一种冠状病毒家族的病毒，源自中国武汉，临床上被称为 COVID-19。虽然传统上被认为是一种呼吸道病毒，但由于 COVID-19 可通过血管紧张素转换酶在全身广泛分布并入侵，因此可能会对多个器官产生影响。COVID-19 引起的神经事件很常见，尤其是在重症患者中，被称为神经 COVID-19。这些事件包括外周和中枢神经系统疾病，如格林-巴利综合征、缺血性中风和各种类型的脑炎。神经 COVID-19 的影响是毁灭性的，通常比非 COVID-19 形式严重得多。免疫抑制或免疫调节治疗通常是治疗的主要方法，例如分别用于脑炎和格林-巴利综合征，而在大多数情况下，管理可能符合常规流程，例如缺血性中风。关于神经 COVID-19 的评估和管理仍有许多需要研究的地方。
