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社区居住老年人自我报告的身体活动特征与20年全因死亡率和心血管疾病死亡率

Self-reported physical activity properties and 20-year all-cause and cardiovascular mortality among community-dwelling older adults.

作者信息

Moshkovits Yonatan, Chetrit Angela, Dankner Rachel

机构信息

Internal Medicine F, Sheba Medical Center, Ramat Gan 52621, Israel.

Public Health Research Center, The Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan 52621, Israel.

出版信息

Postgrad Med J. 2025 Jan 23;101(1192):108-115. doi: 10.1093/postmj/qgae120.

Abstract

PURPOSE

Physical activity was previously associated with decreased mortality. Current guidelines recommend >150 min/week or >75 min/week of moderate or high-intensity exercise to maintain a healthy lifestyle; however, exercise properties most strongly associated with low mortality among the elderly may still be explored.

METHODS

A total of 1210 community-dwelling older adults, from the third phase (1999-2004) of the Israel Study on Glucose Intolerance, Obesity, and Hypertension, were followed until 2016 and 2019 for cardiovascular and all-cause mortality, respectively. Physical activity properties were recorded and evaluated against all-cause and cardiovascular mortality.

RESULTS

Mean age at baseline was 73 ± 7 years, with 638 (53%) females, and 585 (48%) reported habitual exercise. When compared to sedentary individuals, multivariable Cox regressions showed a significantly lower risk for all-cause mortality among currently active individuals [hazard ratio (HR) = 0.72, 95% confidence interval (CI): 0.59-0.88, P = .002], those engaging in light-moderate activity (HR = 0.72, 95% CI: 0.57-0.89, P = .003), those with diverse exercise types (HR = 0.59, 95% CI: 0.44-0.80, P = .001), more sessions/week (HR = 0.94, 95% CI: 0.92-0.97, P < .001), those meeting current exercise recommendations (HR = 0.79, 95% CI: 0.58-0.89, P = .03), those who engaged in walking (HR = 0.58, 95% CI: 0.45-0.76, P < .001), and swimming (HR = 0.66, 95% CI: 0.45-0.96, P = .03). Similar HRs were found for cardiovascular mortality, although a somewhat stronger protective association was observed for swimming (HR = 0.48, 95% CI: 0.24-0.95, P = .04) compared to a sedentary lifestyle.

CONCLUSION

The study further supports current exercise guidelines among the elderly. It also underscores the importance of physical activity in older individuals while prioritizing a greater number of sessions/week in addition to the total duration, and highlights specific activity features associated with lower long-term mortality among older adults. Key message • What is already known on this topic - Physical activity was associated with a lower risk for mortality, although the specific properties and the preferred type of exercise among older adults are still debatable. • What this study adds - The study suggests the optimal activity characteristics in older adults while prioritizing activity sessions over time, light-moderate exercise over strenuous activity, diverse activity, and walking and swimming over other activities. • How this study might affect research, practice or policy - Future exercise guidelines should focus on increasing activity sessions throughout the week and not on the cumulative time to maximize the effect on mortality.

摘要

目的

体力活动此前被认为与死亡率降低有关。当前指南建议每周进行超过150分钟的中等强度运动或超过75分钟的高强度运动以维持健康的生活方式;然而,仍可探索与老年人低死亡率最密切相关的运动特性。

方法

以色列葡萄糖不耐受、肥胖与高血压研究第三阶段(1999 - 2004年)的1210名社区居住老年人分别随访至2016年和2019年,以观察心血管疾病死亡率和全因死亡率。记录体力活动特性,并针对全因死亡率和心血管疾病死亡率进行评估。

结果

基线时的平均年龄为73±7岁,其中638名(53%)为女性,585名(48%)报告有习惯性运动。与久坐不动的个体相比,多变量Cox回归显示,目前仍在运动的个体全因死亡率风险显著较低[风险比(HR)=0.72,95%置信区间(CI):0.59 - 0.88,P = 0.002],进行轻度至中度活动的个体(HR = 0.72,95% CI:0.57 - 0.89,P = 0.003),运动类型多样的个体(HR = 0.59,95% CI:0.44 - 0.80,P = 0.001),每周运动次数更多的个体(HR = 0.94,95% CI:0.92 - 0.97,P < 0.001),符合当前运动建议的个体(HR = 0.79,95% CI:0.58 - 0.89,P = 0.03),进行步行运动的个体(HR = 0.58,95% CI:0.45 - 0.76,P < 0.001),以及进行游泳运动的个体(HR = 0.66,95% CI:0.45 - 0.96,P = 0.03)。心血管疾病死亡率也发现了类似的风险比,尽管与久坐不动的生活方式相比,观察到游泳运动的保护关联更强(HR = 0.48,95% CI:0.24 - 0.95,P = 0.04)。

结论

该研究进一步支持了老年人当前的运动指南。它还强调了体力活动对老年人的重要性,除了总时长外,应优先考虑每周更多的运动次数,并突出了与老年人较低长期死亡率相关的特定活动特征。关键信息•关于该主题已有的认识——体力活动与较低的死亡风险相关,尽管老年人中具体的特性和首选的运动类型仍存在争议。•本研究的补充内容——该研究表明了老年人的最佳活动特征,应优先考虑运动次数而非时长,选择轻度至中度运动而非剧烈运动,进行多样化活动,以及选择步行和游泳而非其他活动。•本研究可能对研究、实践或政策产生的影响——未来的运动指南应侧重于增加每周的运动次数,而非累计时长,以最大限度地提高对死亡率的影响。

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