Ding Ni, Yang Jingjing, Wu Cuiying
Operating Room, Ningbo Medical Center LiHuiLi Hospital, Ningbo, Zhejiang, China.
Department of Cardiac Vascular Surgery, Ningbo Medical Center LiHuiLi Hospital, Ningbo, Zhejiang, China.
PLoS One. 2024 Sep 16;19(9):e0310096. doi: 10.1371/journal.pone.0310096. eCollection 2024.
Prewarming has been recommended to reduce intraoperative hypothermia. However, the evidence is unclear. This review examined if prewarming can prevent intraoperative hypothermia in patients undergoing thoracoscopic and laparoscopic surgeries.
PubMed, CENTRAL, Web of Science, and Embase databases were searched for randomized controlled trials (RCTs) up to 15th January 2024. The primary outcome of interest was the difference in intraoperative core temperature. The secondary outcomes were intraoperative hypothermia (<36°) and postoperative shivering.
Seven RCTs were eligible. Meta-analysis showed that intraoperative core temperature was significantly higher at the start or within 30mins of the start of the surgery (MD: 0.32 95% CI: 0.15, 0.50 I2 = 94% p = 0.0003), 60 mins after the start of the surgery (MD: 0.37 95% CI: 0.24, 0.50 I2 = 81% p<0.00001), 120 mins after the start of the surgery (MD: 0.34 95% CI: 0.12, 0.56 I2 = 88% p = 0.003), and at the end of the surgery (MD: 0.35 95% CI: 0.25, 0.45 I2 = 61% p<0.00001). The incidence of shivering was also significantly lower in the prewarming group (OR: 0.18 95% CI: 0.08, 0.43 I2 = 0%). Prewarming was also associated with a significant reduction in the risk of hypothermia (OR: 0.20 95% CI: 0.10, 0.41 I2 = 0% p<0.0001). The certainty of the evidence assessed by GRADE was "moderate" for intraoperative core temperatures at all time points and "low" for minimal intraoperative core temperature, shivering, and hypothermia.
Moderate to low-quality evidence shows that prewarming combined with intraoperative warming, as compared to intraoperative warming alone, can improve intraoperative temperature control and reduce the risk of hypothermia and shivering in patients undergoing thoracoscopic and laparoscopic procedures.
已推荐进行预加温以减少术中体温过低。然而,证据并不明确。本综述探讨了预加温是否能预防接受胸腔镜和腹腔镜手术患者的术中体温过低。
检索了截至2024年1月15日的PubMed、CENTRAL、Web of Science和Embase数据库中的随机对照试验(RCT)。主要关注的结局是术中核心体温的差异。次要结局是术中体温过低(<36°)和术后寒战。
七项RCT符合条件。荟萃分析表明,在手术开始时或开始后30分钟内术中核心体温显著更高(MD:0.32,95%CI:0.15,0.50;I2 = 94%,p = 0.0003),手术开始后60分钟(MD:0.37,95%CI:0.24,0.50;I2 = 81%,p<0.00001),手术开始后120分钟(MD:0.34,95%CI:0.12,0.56;I2 = 88%,p = 0.003),以及手术结束时(MD:0.35,95%CI:0.25,0.45;I2 = 61%,p<0.00001)。预加温组寒战的发生率也显著更低(OR:0.18,95%CI:0.08,0.43;I2 = 0%)。预加温还与体温过低风险的显著降低相关(OR:0.20,95%CI:0.10,0.41;I2 = 0%,p<0.0001)。GRADE评估的证据确定性对于所有时间点的术中核心体温为“中等”,对于最低术中核心体温、寒战和体温过低为“低”。
中低质量证据表明,与单纯术中加温相比,预加温联合术中加温可改善接受胸腔镜和腹腔镜手术患者的术中体温控制,并降低体温过低和寒战的风险。