毛里求斯果蝇中两个X连锁基因的耦合不稳定性：生殖系和体细胞的突变性。
Coupled instability of two X-linked genes in Drosophila mauritiana: germinal and somatic mutability.
作者信息
Jacobson J W, Hartl D L
出版信息
Genetics. 1985 Sep;111(1):57-65. doi: 10.1093/genetics/111.1.57.
Abstract
A highly unstable allele has been isolated at the white locus of Drosophila mauritiana, a sibling species of D. melanogaster. This allele, white-peach (wpch), mutates spontaneously in males and females to give both wild-type and bleached-white derivatives. The mutation frequency is about 10(-3) mutations/generation. There is no evidence for clustering among mutant progeny, and phenotypically wpch flies with mosaic patches of wild-type tissue in the eyes are frequently recovered. Another X-linked locus, plum, is destabilized when wpch is on the same X chromosome.
摘要
在黑腹果蝇的近缘种毛里求斯果蝇的白眼基因座上分离出了一个高度不稳定的等位基因。这个等位基因，即白桃色（wpch），在雄性和雌性中都会自发突变，产生野生型和漂白白色的衍生物。突变频率约为10（-3）次突变/代。没有证据表明突变后代之间存在聚集现象，并且经常能回收眼睛中带有野生型组织镶嵌斑块的表型为wpch的果蝇。当wpch位于同一条X染色体上时，另一个X连锁基因座，即梅基因，会变得不稳定。
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