Simmons Emma, Gong Jenny, Daskalopoulou Zoe, Quigley Maria A, Alderdice Fiona, Harrison Siân, Fellmeth Gracia
Medical Sciences Division, University of Oxford, Oxford, UK.
National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
BMJ Open. 2024 Sep 16;14(9):e087669. doi: 10.1136/bmjopen-2024-087669.
Maternal suicide is a significant contributor to maternal mortality with devastating consequences for women, families and society. Maternal mortality reporting systems differ across countries and there is no up-to-date overview of maternal suicide deaths globally. This systematic review aims to synthesise the evidence on maternal suicide. The primary objective is to determine the contribution of suicide towards maternal mortality globally and explore differences between geographical regions. The secondary objectives are to summarise the availability and quality of data globally and to describe how suicide deaths are classified across different countries.
This protocol follows the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. Medline, Embase, PsycINFO, Global Health and CINAHL databases and the grey literature were searched with no date or language restrictions. Observational studies, national surveys and reports that present data on maternal deaths due to suicide occurring during pregnancy, intrapartum and in the postpartum period will be included. Screening, data extraction and quality assessment will be conducted independently by two reviewers. Results will be summarised narratively. If sufficient outcome data are available, random-effects meta-analyses will be conducted to determine global pooled estimates of suicide-related maternal mortality rates and the proportion of maternal deaths attributable to suicide.
Ethical approval is not required for this systematic review. Results will be written up for publication in a peer-reviewed journal and findings will be shared at national and international conferences.
CRD42023429072.
孕产妇自杀是孕产妇死亡的一个重要原因，给妇女、家庭和社会带来了毁灭性后果。各国的孕产妇死亡报告系统各不相同，目前尚无全球孕产妇自杀死亡情况的最新概述。本系统评价旨在综合关于孕产妇自杀的证据。主要目标是确定自杀对全球孕产妇死亡的贡献，并探讨不同地理区域之间的差异。次要目标是总结全球数据的可得性和质量，并描述不同国家如何对自杀死亡进行分类。
本方案遵循系统评价与Meta分析方案的首选报告项目指南。对Medline、Embase、PsycINFO、全球健康和CINAHL数据库以及灰色文献进行检索，无日期或语言限制。将纳入观察性研究、全国性调查和报告，这些研究和报告提供了孕期、分娩期和产后因自杀导致的孕产妇死亡数据。筛选、数据提取和质量评估将由两名评审员独立进行。结果将进行叙述性总结。如果有足够的结局数据，将进行随机效应Meta分析，以确定与自杀相关的孕产妇死亡率的全球汇总估计值以及自杀所致孕产妇死亡的比例。
本系统评价无需伦理批准。结果将撰写成文章发表在同行评审期刊上，并在国内和国际会议上分享研究结果。
PROSPERO注册号：CRD42023429072。
