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1
EBM BLS: In Older Patients with Treatment-Resistant Depression, Adding Aripiprazole to Current Antidepressant Increased Psychological Well-Being and Depression Remission Rates.循证医学基础生命支持：在老年难治性抑郁症患者中，在当前抗抑郁药基础上加用阿立哌唑可提高心理健康水平和抑郁缓解率。
J Gen Intern Med. 2025 Feb;40(2):511-512. doi: 10.1007/s11606-024-08995-1. Epub 2024 Sep 16.
2
Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents.心理治疗与抗抑郁药物单独及联合使用治疗儿童和青少年抑郁症
Cochrane Database Syst Rev. 2012 Nov 14;11:CD008324. doi: 10.1002/14651858.CD008324.pub2.
3
Psychological therapies for treatment-resistant depression in adults.成人难治性抑郁症的心理治疗
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4
Pramipexole Augmentation for Treatment-Resistant Unipolar Depression Not Responding to Aripiprazole Augmentation: An Observational Study.普拉克索增效治疗对阿立哌唑增效无反应的难治性单相抑郁症：一项观察性研究。
J Clin Psychopharmacol. 2025;45(3):236-242. doi: 10.1097/JCP.0000000000001986. Epub 2025 Apr 1.
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial.普拉克索联合心境稳定剂治疗难治性双相抑郁：PAX - BD随机双盲安慰剂对照试验
Health Technol Assess. 2025 May;29(21):1-216. doi: 10.3310/HBFC1953.
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Psychological and pharmacological interventions for depression in patients with coronary artery disease.冠心病患者抑郁的心理和药理学干预措施。
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Continuation and maintenance treatments for depression in older people.老年人抑郁症的延续治疗和维持治疗。
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本文引用的文献

1
Antidepressant Augmentation versus Switch in Treatment-Resistant Geriatric Depression.抗抑郁药增效与治疗抵抗性老年抑郁症的转换治疗。
N Engl J Med. 2023 Mar 23;388(12):1067-1079. doi: 10.1056/NEJMoa2204462. Epub 2023 Mar 3.
2
Efficacy, safety, and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in late life: a randomised, double-blind, placebo-controlled trial.阿立哌唑强化药物治疗对老年难治性抑郁症的疗效、安全性及耐受性：一项随机、双盲、安慰剂对照试验
Lancet. 2015 Dec 12;386(10011):2404-12. doi: 10.1016/S0140-6736(15)00308-6. Epub 2015 Sep 27.
3
Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report.需要一个或多个治疗步骤的抑郁症门诊患者的急性和长期转归：STAR*D报告
Am J Psychiatry. 2006 Nov;163(11):1905-17. doi: 10.1176/ajp.2006.163.11.1905.
4
The prevalence of psychiatric disorders in a primary care practice.基层医疗实践中精神障碍的患病率。
Arch Gen Psychiatry. 1988 Dec;45(12):1100-6. doi: 10.1001/archpsyc.1988.01800360048007.

EBM BLS: In Older Patients with Treatment-Resistant Depression, Adding Aripiprazole to Current Antidepressant Increased Psychological Well-Being and Depression Remission Rates.

作者信息

Fuest Stephen, Jackson Christopher D, Wheeler Stephanie G B

机构信息

University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.

University of Tennessee Health Science Center, Memphis, TN, USA.

出版信息

J Gen Intern Med. 2025 Feb;40(2):511-512. doi: 10.1007/s11606-024-08995-1. Epub 2024 Sep 16.

DOI:10.1007/s11606-024-08995-1
PMID:39285074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11802936/
Abstract
摘要