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类风湿关节炎患者的继发性干燥综合征:一例病例报告及文献复习

Secondary Sjögren's syndrome in a rheumatoid arthritis patient: A case report and review of literature.

作者信息

Hussein Abdulaziz, Gareeballah Awadia, Hamd Zuhal Y, Elzaki Maisa, Abouraida Raga Ahmed, Eltahir Mohamed Abdalla, Khogaly Mariam, Alsharif Walaa, Hamad Ali A

机构信息

University of Medical Science and Technology, Graduate College, Khartoum, Sudan.

Department of Diagnostic Radiology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia.

出版信息

Radiol Case Rep. 2024 Sep 4;19(11):5513-5518. doi: 10.1016/j.radcr.2024.07.196. eCollection 2024 Nov.

DOI:10.1016/j.radcr.2024.07.196
PMID:39285982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11403904/
Abstract

Secondary Sjogren's syndrome (sSS) is a medical condition that occurs in individuals with autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis. It predominantly affects females rather than males. We present a case of a 32-year-old female with a 3-year history of rheumatoid arthritis (RA) who presented to the internal medicine and rheumatology clinic with several complaints, including swelling and tenderness in her left jaw, dry mouth (xerostomia), irritated eyes (xerophthalmia), severe joint pain, and a decreased in saliva production. The blood tests demonstrate the presence of anti-SSA and anti-SSB autoantibodies and elevation of total leukocyte count (TLC), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels, indicating inflammation. A high-frequency ultrasound confirmed the diagnosis of Secondary Sjogren's syndrome grade II, specifically affecting the left parotid gland (PG).

摘要

继发性干燥综合征(sSS)是一种发生于患有自身免疫性疾病(如系统性红斑狼疮(SLE)和类风湿关节炎)的个体的病症。它主要影响女性而非男性。我们报告一例32岁女性病例,该患者有3年类风湿关节炎(RA)病史,因多种症状前往内科和风湿病诊所就诊,包括左颌肿胀和压痛、口干(口干燥症)、眼涩(干眼症)、严重关节疼痛以及唾液分泌减少。血液检查显示存在抗SSA和抗SSB自身抗体,总白细胞计数(TLC)、红细胞沉降率(ESR)和C反应蛋白(CRP)水平升高,提示有炎症。高频超声确诊为二级继发性干燥综合征,具体累及左侧腮腺(PG)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f076/11403904/3a5089204b25/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f076/11403904/4dbcbecea247/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f076/11403904/20fc7380192b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f076/11403904/3a5089204b25/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f076/11403904/4dbcbecea247/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f076/11403904/20fc7380192b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f076/11403904/3a5089204b25/gr3.jpg

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本文引用的文献

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Using transfer learning-based causality extraction to mine latent factors for Sjögren's syndrome from biomedical literature.利用基于迁移学习的因果关系提取从生物医学文献中挖掘干燥综合征的潜在因素。
Heliyon. 2023 Aug 22;9(9):e19265. doi: 10.1016/j.heliyon.2023.e19265. eCollection 2023 Sep.
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First report of rheumatoid arthritis and secondary Sjögren's syndrome complicated with heart failure.类风湿关节炎和继发性干燥综合征并发心力衰竭的首例报告。
Clin Case Rep. 2021 Aug 11;9(8):e04581. doi: 10.1002/ccr3.4581. eCollection 2021 Aug.
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Diagnostic Performances of Ultrasound Evaluation of Major Salivary Glands According to the 2019 Outcome Measures in Rheumatology Ultrasound Scoring System.
2019 年风湿病超声评分系统结局测量标准对大唾液腺超声评估的诊断性能。
Arthritis Care Res (Hoboken). 2022 Nov;74(11):1924-1932. doi: 10.1002/acr.24631. Epub 2022 Aug 5.
4
Patient-based reliability of the Outcome Measures in Rheumatology (OMERACT) ultrasound scoring system for salivary gland assessment in patients with Sjögren's syndrome.基于患者的干燥综合征患者唾液腺评估的风湿病学结局测量(OMERACT)超声评分系统的可靠性。
Rheumatology (Oxford). 2021 May 14;60(5):2169-2176. doi: 10.1093/rheumatology/keaa471.
5
Ultrasound-guided core needle biopsy compared with open biopsy: a new diagnostic approach to salivary gland enlargement in Sjögren's syndrome?超声引导下核心针活检与开放活检:干燥综合征唾液腺肿大的新诊断方法?
Rheumatology (Oxford). 2021 Mar 2;60(3):1282-1290. doi: 10.1093/rheumatology/keaa441.
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Laryngoscope. 2021 Jan;131(1):E83-E89. doi: 10.1002/lary.28742. Epub 2020 May 15.
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Arthritis Care Res (Hoboken). 2021 Jun;73(6):849-855. doi: 10.1002/acr.24203.
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