Zacur H A, Genadry R, Rock J A, King T M, Smith B R, Foster G V
J Clin Endocrinol Metab. 1985 Oct;61(4):787-9. doi: 10.1210/jcem-61-4-787.
Pressure studies were carried out in 10 women to determine whether TRH stimulates muscular contractions in the genitourinary system. TRH (500 micrograms) or saline was administered iv as a bolus injection. Whereas saline had no effect, TRH increased intraurethral pressures in all women, vaginal pressure in 7, and bladder pressure in none. These findings suggest that TRH, acting centrally, peripherally, or both, may play a role in initiating muscular contractions in the female genitourinary tract.
对10名女性进行了压力研究，以确定促甲状腺激素释放激素（TRH）是否会刺激泌尿生殖系统的肌肉收缩。TRH（500微克）或生理盐水以静脉推注的方式给药。生理盐水无作用，而TRH使所有女性的尿道内压升高，7名女性的阴道压升高，无一例膀胱压升高。这些发现表明，TRH可能通过中枢、外周或两者兼有的作用，在引发女性泌尿生殖道的肌肉收缩中发挥作用。
