Bickel M, Munoz J L, Giovannini P
J Dent Res. 1985 Oct;64(10):1218-20. doi: 10.1177/00220345850640100801.
The pH of human gingival crevicular fluid (GCF) has been reported by many authors to be very alkaline (pH 7.5 - 8.7). This alkalinity could be explained, at least partially, by the fact that all measurements were performed either at low PCO2 or in the absence of CO2. Therefore, we set up a procedure which allows for measurement of the pH of GCF samples from single inflamed sites at controlled PCO2. At a PCO2 of 4.7 kPa (= 35 mmHg) and at 37 degrees C, the pH was 7.96 +/- 0.10 (SEM, n = 9), a value which differs significantly from the value of 8.38 +/- 0.09 measured in the absence of CO2 in the same samples. The non-bicarbonate buffer value of the sample determined by CO2 titration was 6.0 slykes. It is because this value is low that pH varies so greatly with PCO2. At physiological PCO2, the total buffering power becomes very high above pH 8.0, because of the high bicarbonate concentration.
许多作者报告称，人龈沟液（GCF）的pH值呈强碱性（pH 7.5 - 8.7）。这种碱性至少可以部分解释为，所有测量均在低二氧化碳分压或无二氧化碳的条件下进行。因此，我们建立了一种方法，可在控制二氧化碳分压的条件下测量单个炎症部位的龈沟液样本的pH值。在二氧化碳分压为4.7 kPa（= 35 mmHg）且温度为37摄氏度时，pH值为7.96 +/- 0.10（标准误，n = 9），该值与在相同样本无二氧化碳条件下测得的8.38 +/- 0.09有显著差异。通过二氧化碳滴定法测定的样本非碳酸氢盐缓冲值为6.0斯莱克。正是因为该值较低，pH值才会随二氧化碳分压变化如此之大。在生理二氧化碳分压下，由于碳酸氢盐浓度较高，pH值高于8.0时总缓冲能力变得非常高。
