Third Department of Surgery, Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Medicine (Baltimore). 2024 Sep 13;103(37):e39633. doi: 10.1097/MD.0000000000039633.
Retroperitoneal liposarcoma is a rare and complex tumor originating from the mesenchymal tissues, with no specific manifestations in the early stage, and a large tumor size in the late stage. Patients often consult a physician because of large abdominal mass, increased abdominal circumference, and abdominal pain, and rarely because of leukocytosis.
A 54-year-old female presented to our hospital with complaints of "abdominal distension for over 3 months, left lumbar pain for over 2 months." Considering the comprehensive symptoms, examinations, computed tomography scans, and pathological results, the possibility of retroperitoneal liposarcoma is high.
Retroperitoneal liposarcoma with leukocytosis.
Open retroperitoneal mass excision along with transcystoscopic left ureteral Double-J Ureterl Stent Insertion tube placement and left nephrectomy.
The postoperative pathological findings of the abdominal mass, combined with morphological and immunohistochemical results, are consistent with retroperitoneal liposarcoma. The patient had no recurrence in 7 months of postoperative follow-up conducted on the telephone and is now in continued follow-up.
Retroperitoneal liposarcoma is highly malignant and prone to recurrence. Radical surgery is currently the primary treatment modality for patients with this condition. Analogous to cancer patients, those with elevated white blood cell counts and retroperitoneal liposarcoma may have poor prognoses, with a high likelihood of local recurrence and distant metastasis. Close postoperative follow-up is necessary. Therefore, regular postoperative review of blood routine may be a relatively economical and convenient method for the early detection of recurrence and metastasis of retroperitoneal liposarcoma.
腹膜后脂肪肉瘤是一种罕见且复杂的肿瘤,起源于间叶组织,早期无特异性表现,晚期肿瘤体积较大。患者常因巨大的腹部肿块、腰围增大和腹痛就诊,很少因白细胞增多就诊。
一名 54 岁女性因“腹胀 3 个月余,左腰痛 2 个月余”来我院就诊。综合症状、检查、CT 扫描和病理结果,高度怀疑腹膜后脂肪肉瘤。
腹膜后脂肪肉瘤伴白细胞增多。
行开放腹膜后肿块切除术,并经膀胱镜行左输尿管双 J 管置入术和左肾切除术。
术后腹部肿块的病理检查结果,结合形态学和免疫组化结果,均符合腹膜后脂肪肉瘤。术后 7 个月电话随访患者无复发,目前仍在持续随访中。
腹膜后脂肪肉瘤恶性程度高,易复发。根治性手术是目前此类患者的主要治疗方法。类似于癌症患者,白细胞计数升高和腹膜后脂肪肉瘤患者的预后可能较差,局部复发和远处转移的可能性较高。需要密切的术后随访。因此,定期进行术后血常规复查可能是一种相对经济、方便的方法,可以早期发现腹膜后脂肪肉瘤的复发和转移。