Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Korea.
Department of Neurology, Kyungpook National University Hospital, Daegu, Korea.
Medicine (Baltimore). 2024 Sep 13;103(37):e39689. doi: 10.1097/MD.0000000000039689.
During the coronavirus disease of 2019 (COVID-19) pandemic, various movement disorders associated with COVID-19 infection have been reported. However, the incidence of dystonia specifically associated with COVID-19 infection has been particularly rare.
A 43-year-old male patient presented to the movement disorders clinic with complaints of facial grimacing while chewing and experiencing spasms during nasal breathing. These symptoms appeared 2 weeks after he tested positive for COVID-19.
Based on normal diagnostic test results, including brain imaging and blood tests, it was concluded that task-specific facial dystonia following COVID-19 infection.
Despite treatment with clonazepam, trihexyphenidyl, and carbamazepine, his condition did not improve. Subsequently, botulinum toxin injections were administered to the affected facial muscles identified through video analysis.
Botulinum toxin injections led to a significant improvement in the patient's symptoms.
Task-specific dystonia affecting the facial muscles, particularly induced by specific actions such as chewing and nasal breathing, is rare and may represent an atypical post-infectious manifestation of COVID-19.
在 2019 年冠状病毒病(COVID-19)大流行期间,已报告了多种与 COVID-19 感染相关的运动障碍。然而,与 COVID-19 感染具体相关的肌张力障碍的发生率特别罕见。
一名 43 岁男性患者因咀嚼时面部抽搐和面鼻呼吸时痉挛而到运动障碍门诊就诊。这些症状在 COVID-19 检测呈阳性后 2 周出现。
基于正常的诊断测试结果,包括脑部成像和血液检查,诊断为 COVID-19 感染后出现任务特异性面肌痉挛。
尽管使用氯硝西泮、苯海索和卡马西平进行了治疗,但他的病情并未改善。随后,通过视频分析对受累的面肌进行了肉毒毒素注射。
肉毒毒素注射显著改善了患者的症状。
咀嚼和面鼻呼吸等特定动作诱发的累及面肌的任务特异性肌张力障碍罕见,可能代表 COVID-19 的一种非典型感染后表现。