Cala A, Ferasin L, Ferasin H, Domenech O, Bini M, Valenti V, Venco L
Specialist Veterinary Cardiology Consultancy at The Ralph Veterinary Referral Centre, Marlow SL7 1YG, UK.
Specialist Veterinary Cardiology Consultancy at The Ralph Veterinary Referral Centre, Marlow SL7 1YG, UK.
J Vet Cardiol. 2024 Dec;56:23-34. doi: 10.1016/j.jvc.2024.08.005. Epub 2024 Aug 19.
Successful closure of patent ductus arteriosus (PDA) can be obtained with surgical ligation or with occlusion via minimally invasive per-catheter techniques. This study was performed to assess feasibility and effectiveness of transjugular PDA occlusion in dogs weighing < 3 kg with a device called Nit-Occlud® PDA.
Thirteen client-owned dogs.
This was a retrospective study. Clinical records of dogs that underwent PDA occlusion with a Nit-Occlud® PDA were reviewed. Data collection included patients' signalment, clinical findings, pre- and post-procedure echocardiographic measurements, device size, procedure time and clinical outcome.
The median age of these patients was six months (2.5-38.0 months), with a mean body weight of 2.44 ± 0.43 kg. The mean minimal ductal diameter (MDD) was 1.82 ± 0.43 mm, while the mean ampulla diameter (AD) was 5.51 ± 1.89 mm. Duct closure was successful in 12 cases. Minimal or no residual shunt was observed on echocardiography prior to device release. In one dog, the device was not released owing to unsatisfactory occlusion, prompting an alternative occlusion method. Follow-up echocardiographic examinations showed complete ductal closure and reversed cardiac remodelling in all cases where the device was successfully released.
The Nit-Occlud® is deployed through a delivery system with an outer diameter of 4 Fr or 5 Fr, which makes this solution particularly attractive in patients where vascular access is challenging or unfeasible due to the small size of their vessels.
The Nit-Occlud® PDA appears a feasible and effective occlusion system in small patients weighing <3 kg.
动脉导管未闭（PDA）可通过手术结扎或经皮微创导管技术封堵成功闭合。本研究旨在评估使用名为Nit-Occlud® PDA的装置对体重<3 kg的犬经颈静脉封堵PDA的可行性和有效性。
13只客户拥有的犬。
这是一项回顾性研究。回顾了使用Nit-Occlud® PDA封堵PDA的犬的临床记录。数据收集包括患者的特征、临床发现、术前和术后超声心动图测量、装置尺寸、手术时间和临床结果。
这些患者的中位年龄为6个月（2.5 - 38.0个月），平均体重为2.44 ± 0.43 kg。平均最小导管直径（MDD）为1.82 ± 0.43 mm，而平均壶腹直径（AD）为5.51 ± 1.89 mm。12例封堵成功。在释放装置前，超声心动图观察到最小或无残余分流。在1只犬中，由于封堵效果不理想未释放装置，促使采用替代封堵方法。随访超声心动图检查显示，在成功释放装置的所有病例中，导管完全闭合且心脏重塑逆转。
Nit-Occlud®通过外径为4 Fr或5 Fr的输送系统部署，这使得该解决方案在因血管细小而血管通路具有挑战性或不可行的患者中特别有吸引力。
Nit-Occlud® PDA在体重<3 kg的小型患者中似乎是一种可行且有效的封堵系统。
