Hicks Rodney J, Ware Robert E, Callahan Jason
The Melbourne Theranostic Innovation Centre, North Melbourne, Victoria 3051, Australia; St Vincent's Hospital, Department of Medicine, The University of Melbourne, Fitzroy, Victoria 3065, Australia.
The Melbourne Theranostic Innovation Centre, North Melbourne, Victoria 3051, Australia.
Semin Nucl Med. 2025 Jan;55(1):11-20. doi: 10.1053/j.semnuclmed.2024.07.003. Epub 2024 Sep 17.
PET/CT devices with an axial field-of-view (FOV) of 1 m allow simultaneous imaging from the head to the upper thighs, the typical axial extent of many "whole-body" oncological studies acquired by moving a patient sequentially through a conventional FOV device, or rapid total-body imaging using the same approach. Increasing the FOV to around 2 m provides true simultaneous total-body imaging. Either approach dramatically increases the sensitivity for detection of annihilation events arising within the body. For the purposes of this review, both configurations are considered to represent "total-body" PET/CT devices because they share both advantages and disadvantages. These pros and cons are discussed in the context of both clinical and research applications from a patient and institutional perspective.
轴向视野（FOV）为1米的PET/CT设备能够同时对从头部到大腿上部进行成像，这也是许多“全身”肿瘤学研究的典型轴向范围，这些研究是通过让患者依次穿过传统视野设备来获取的，或者采用相同方法进行快速全身成像。将视野增加到约2米可实现真正的同时全身成像。这两种方法都能显著提高对体内湮灭事件的检测灵敏度。在本综述中，这两种配置都被视为“全身”PET/CT设备，因为它们有共同的优缺点。从患者和机构的角度，在临床和研究应用的背景下对这些优缺点进行了讨论。
