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Shouldice 与 Lichtenstein 腹股沟疝修补术的比较:一项随机对照试验的荟萃分析。

Shouldice versus Lichtenstein inguinal hernia repair: A meta-analysis of randomized controlled trials.

机构信息

Department of General Surgery, Heliopolis Hospital, São Paulo, Brazil.

USCS - University of São Caetano do Sul, São Paulo, Brazil.

出版信息

World J Surg. 2024 Nov;48(11):2604-2614. doi: 10.1002/wjs.12352. Epub 2024 Sep 17.

Abstract

BACKGROUND

The Lichtenstein technique is the standard treatment for adult open inguinal hernia repair. Among the non-mesh repair techniques, Shouldice has shown the best results and is comparable to mesh repairs in selected cases. Due to the risk of chronic groin pain associated with the Lichtenstein technique, Shouldice has increased in popularity, and some surgeons have adopted it as a viable first-line option.

METHODS

MEDLINE, Cochrane, Central Register of Clinical Trials, and EMBASE for randomized controlled trials (RCT) published until February 2024. Risk ratios (RRs) with 95% confidence intervals (CIs) were pooled using a random-effects model. Heterogeneity was assessed using the Cochran Q test and I statistics with p-values <0.10 and I > 25% considered significant. Statistical analysis was performed using R Software, version 4.1.2.

RESULTS

Fourteen RCTs comprising 2784 patients were included, of whom 1379 (47.5%) were submitted to the Shouldice hernia repair and 1513 (52.5%) to the Lichtenstein technique. Shouldice was associated with a significant increase in the recurrence rate (4.2% vs. 0.9%; RR 3.68; 95% CI 2.05-6.60; p < 0.001; I = 0%) compared with Lichtenstein. The number needed to treat (NNT) to prevent one Shouldice recurrence was 30.3. There were no significant differences between groups in chronic pain, urinary retention, bladder injury, testicular atrophy, wound infection, hematoma-seroma, or hypesthesia.

CONCLUSION

The Lichtenstein technique was associated with reduced recurrence rates compared with Shouldice in patients undergoing inguinal hernia repair. However, the overall recurrence rate with the Shouldice technique was still low (4.2%), suggesting that it may be a viable option in selected patients.

摘要

背景

Lichtenstein 技术是成人开放式腹股沟疝修补术的标准治疗方法。在非网片修补技术中,Shouldice 技术显示出最佳的结果,并且在某些情况下可与网片修补相媲美。由于与 Lichtenstein 技术相关的慢性腹股沟疼痛风险,Shouldice 技术的应用日益增多,一些外科医生已将其作为可行的一线选择。

方法

检索 MEDLINE、Cochrane、Central Register of Clinical Trials 和 EMBASE 中截至 2024 年 2 月发表的随机对照试验(RCT)。使用随机效应模型汇总风险比(RR)及其 95%置信区间(CI)。使用 Cochran Q 检验和 I 统计量评估异质性,当 p 值<0.10 和 I > 25%时认为差异有统计学意义。使用 R 软件,版本 4.1.2 进行统计分析。

结果

纳入了 14 项 RCT,共包含 2784 例患者,其中 1379 例(47.5%)接受了 Shouldice 疝修补术,1513 例(52.5%)接受了 Lichtenstein 技术。与 Lichtenstein 技术相比,Shouldice 技术的复发率显著增加(4.2%比 0.9%;RR 3.68;95%CI 2.05-6.60;p<0.001;I=0%)。预防一例 Shouldice 复发需要治疗的人数(NNT)为 30.3。两组在慢性疼痛、尿潴留、膀胱损伤、睾丸萎缩、伤口感染、血肿-血清肿或感觉迟钝方面无显著差异。

结论

与 Lichtenstein 技术相比,在接受腹股沟疝修补术的患者中,Lichtenstein 技术与较低的复发率相关。然而,Shouldice 技术的总体复发率仍然较低(4.2%),这表明在某些患者中,它可能是一种可行的选择。

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