Kogire M, Yoshida A, Noda H, Asano M, Yamada T, Kitamura O, Matsumoto M
Gan No Rinsho. 1985 Jun;31(7):865-9.
A 47-year-old man was admitted because of a left axillary tumor. A biopsy of the tumor disclosed adenocarcinoma. The bone survey showed multiple sclerotic metastases. Thirteen months after his first admission, a left breast tumor developed and a simple mastectomy revealed a papillotubular carcinoma. Skin metastases appeared postoperatively and were exacerbated with accumulation of pericardial effusion and a high CEA level (401.7 ng/ml) despite radiation and chemotherapy. Estrogen therapy with diethylstilbestrol sodium phosphate was started, resulting in the disappearance of pericardial effusion and skin metastases. The patient remains well 10 months after starting estrogen therapy with a normal CEA level.
一名47岁男性因左腋窝肿瘤入院。肿瘤活检显示为腺癌。骨扫描显示有多处硬化性转移。首次入院13个月后，左侧乳腺出现肿瘤，单纯乳房切除术显示为乳头管状癌。术后出现皮肤转移，尽管进行了放疗和化疗，但心包积液增多且癌胚抗原（CEA）水平升高（401.7 ng/ml），病情加重。开始使用磷酸己烯雌酚进行雌激素治疗，结果心包积液和皮肤转移消失。开始雌激素治疗10个月后，患者情况良好，CEA水平正常。
