School of Public Health, the key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, No. 6 Ankang Road Guian New District, Guiyang, 561113, China.
Department of Sleep Medicine, the Second People's Hospital of Guizhou Province, Guiyang, China.
BMC Public Health. 2024 Sep 17;24(1):2530. doi: 10.1186/s12889-024-20054-2.
Sleep regularity has been linked to a risk of arterial stiffness (AS). However, the association between sleep regularity indicators, which reflect 24-hour sleep variability, and AS has not yet been examined.
We analyzed data from 516 adults, aged 40-65 years (the median age of 51 years), from the 'Follow-up Study of Sleep Characteristics and Chronic Diseases in the Middle-aged and Elderly Population in Guizhou Province'. Participants underwent assessments of AS (OMRON HBP-8000, baPWV ≥ 1400 cm/s) and sleep (wrist smart band (Honor band 5i) for ≥ 7 days). Logistic regression was utilized to evaluate the odds ratio (OR) and 95% confidence interval (CI) of the association between sleep regularity and AS.
A total of 516 people were included in this study, of which 279 (54.07%) were in the AS group. The univariate results showed that the AS group (Median 71.18) had lower SRI compared to the No-AS group (Median 75.00) (p < 0.001). The multifactorial results showed participants with higher SRI scores were more likely to have a lower risk of AS compared to those with lower SRI scores (OR=0.46, 95%CI: 0.25-0.85, p = 0.013). The SRI effect was more pronounced in male (OR=0.28, 95%CI: 0.12-0.69, p = 0.005), snoring populations (OR=0.13, 95%CI: 0.04-0.48, p = 0.002), and non-retired populations (OR=0.45, 95%CI: 0.22-0.92, p = 0.028).
The present findings indicated that the effect between SRI and AS may be more sensitive than the standard deviation of sleep duration as well as the standard deviation of sleep onset.
睡眠规律性与动脉僵硬度（AS）风险有关。然而，反映 24 小时睡眠变异性的睡眠规律性指标与 AS 之间的关系尚未被研究过。
我们分析了来自贵州省中年和老年人群睡眠特征和慢性病随访研究的 516 名年龄在 40-65 岁（中位年龄 51 岁）的成年人的数据。参与者接受了 AS（欧姆龙 HBP-8000，baPWV≥1400cm/s）和睡眠（手腕智能带（Honor band 5i）≥7 天）的评估。采用逻辑回归评估睡眠规律性与 AS 之间的关联的比值比（OR）和 95%置信区间（CI）。
共有 516 人纳入本研究，其中 279 人（54.07%）为 AS 组。单变量结果显示，AS 组（中位数 71.18）的 SRI 低于无 AS 组（中位数 75.00）（p<0.001）。多因素结果显示，与 SRI 评分较低的参与者相比，SRI 评分较高的参与者发生 AS 的风险较低（OR=0.46，95%CI：0.25-0.85，p=0.013）。SRI 的影响在男性（OR=0.28，95%CI：0.12-0.69，p=0.005）、打鼾人群（OR=0.13，95%CI：0.04-0.48，p=0.002）和非退休人群（OR=0.45，95%CI：0.22-0.92，p=0.028）中更为显著。
本研究结果表明，SRI 与 AS 之间的关系可能比睡眠时间标准差和睡眠潜伏期标准差更为敏感。
