米尔梅拉诺酮G，一种从红树林来源的真菌GXIMD 03004中分离出的半萜烯。

Millmerranones G, a meroterpene isolated from a mangrove-derived fungus sp. GXIMD 03004.

作者信息

Cao Guang-Ping, Huang Guo-Qiang, Chen Guang-Ying, Yi Xiang-Xi, Wang Xue-Sheng, Wei Feng-Jiao, Zhu Cai-Qiong, Gao Cheng-Hai, Liu Yong-Hong, Bai Meng

机构信息

Guangxi Key Laboratory of Marine Drugs, Guangxi University of Chinese Medicine, Nanning, China.

Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning, China.

出版信息

Nat Prod Res. 2024 Sep 17:1-7. doi: 10.1080/14786419.2024.2402460.

DOI:10.1080/14786419.2024.2402460

PMID:39289879

Abstract

One new meroterpene derivative, millmerranones G (), and three known analogues (-) were identified from the mangrove-derived fungus sp. GXIMD 03004, which was isolated from the leaves of mangrove L. collected from Beibu Gulf in China. The structure of was characterised by a comprehensive interpretation of the NMR spectroscopic and HRESIMS data. The absolute configuration for was established using experimental and calculated ECD data. The anti- activities of all compounds were evaluated, the result showed that compounds and has weak activity against .

摘要

从中国北部湾采集的红树植物L.的叶子中分离得到的红树林来源真菌GXIMD 03004中，鉴定出一种新的半萜衍生物，密勒酮G（），以及三种已知类似物（-）。通过对核磁共振光谱和高分辨电喷雾电离质谱数据的综合解析确定了的结构。利用实验和计算的电子圆二色光谱数据确定了的绝对构型。评估了所有化合物的抗菌活性，结果表明化合物和对具有较弱的活性。