Timirau Wendy M, Sari Esra, Shahid Maham, Guzman Nilmarie, Villegas Augusto
HCA Florida Orange Park Hospital, Orange Park, FL.
HCA Healthc J Med. 2024 Aug 1;5(4):469-472. doi: 10.36518/2689-0216.1684. eCollection 2024.
Idiopathic granulomatous mastitis (IGM), also known as nonpuerperal mastitis or granulomatous lobular mastitis, is a rare, benign, chronic inflammatory breast disease first characterized in 1972. IGM is characterized by sterile noncaseating lobulocentric granulomatous inflammation, usually affecting parous premenopausal women with a history of lactation.
We present a 38-year-old African American woman presenting to our continuity clinic complaining of a painful right breast mass discovered during a self-breast examination. An initial right breast ultrasound demonstrated an area of concern with asymmetry, architectural distortion, and a questionable mass correlating to a 5.1 cm hypoechoic mass at the 12:30 position. Additionally, a mammogram showed a suspicious, indeterminate, large hypoechoic region or mass with angular margins measuring 5.1 x 1.7 x 3.7 cm with slight internal vascularity. An ultrasound-guided stereotactic biopsy revealed extensive mixed inflammatory and focal granulomatous lobular mastitis.
Idiopathic granulomatous mastitis is a rare disorder that often mimics breast malignancies and infectious processes. This case highlights the need for further research on IGM pathogenesis to prevent unnecessary life-altering therapeutic procedures and bring awareness to the medical community.
特发性肉芽肿性乳腺炎(IGM),也称为非产褥期乳腺炎或肉芽肿性小叶性乳腺炎,是一种罕见的良性慢性炎症性乳腺疾病,于1972年首次被描述。IGM的特征是无菌性非干酪样小叶中心性肉芽肿性炎症,通常影响有哺乳史的经产绝经前女性。
我们报告一名38岁非裔美国女性,她到我们的连续性诊所就诊,主诉在自我乳房检查时发现右乳疼痛性肿块。最初的右乳超声显示一个可疑区域,有不对称、结构扭曲,以及一个可疑肿块,对应于12点30分位置的一个5.1厘米低回声肿块。此外,乳房X线摄影显示一个可疑的、不确定的、大的低回声区域或肿块,边缘呈角状,大小为5.1×1.7×3.7厘米,内部有轻微血管。超声引导下的立体定向活检显示广泛的混合性炎症和局灶性肉芽肿性小叶性乳腺炎。
特发性肉芽肿性乳腺炎是一种罕见疾病,常模仿乳腺恶性肿瘤和感染性病变。该病例强调需要对IGM的发病机制进行进一步研究,以避免不必要的改变生活的治疗程序,并提高医学界的认识。