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特发性肉芽肿性乳腺炎:病例报告及文献综述

Idiopathic granulomatous mastitis: case report and review of the literature.

作者信息

Imoto S, Kitaya T, Kodama T, Hasebe T, Mukai K

机构信息

Department of Surgery, National Cancer Center Hospital East, Chiba, Japan.

出版信息

Jpn J Clin Oncol. 1997 Aug;27(4):274-7. doi: 10.1093/jjco/27.4.274.

Abstract

We report a case of idiopathic granulomatous mastitis in a 35-year-old Japanese woman, who came to our hospital complaining of a tender mass in her right breast. Because the results of initial aspiration cytology were considered highly suspicious for carcinoma, modified radical mastectomy was performed. However, the final histological diagnosis was granulomatous lobular mastitis with no evidence of malignancy. Idiopathic granulomatous mastitis is a rare inflammatory breast disease of unknown etiology. Since the clinical manifestations are similar to those of mammary carcinoma, this condition has been misdiagnosed as carcinoma and treated as such. A review of the literature revealed that idiopathic granulomatous mastitis has tended to occur in young patients with a history of childbirth or oral contraceptive usage. Clinical or imaging diagnosis has often been difficult. Complete resection or corticosteroid therapy can be recommended as the optimal treatment. Since 38% of patients experience recurrence, long-term follow-up is indicated.

摘要

我们报告一例35岁日本女性特发性肉芽肿性乳腺炎病例,该患者因右乳出现压痛性肿块前来我院就诊。由于初次穿刺细胞学检查结果高度怀疑为癌,遂行改良根治性乳房切除术。然而,最终组织学诊断为肉芽肿性小叶乳腺炎,未发现恶性证据。特发性肉芽肿性乳腺炎是一种病因不明的罕见炎性乳腺疾病。由于其临床表现与乳腺癌相似,该病常被误诊为癌并按此进行治疗。文献回顾显示,特发性肉芽肿性乳腺炎倾向于发生在有分娩史或使用口服避孕药史的年轻患者中。临床或影像学诊断往往困难。可推荐完整切除或皮质类固醇治疗作为最佳治疗方法。由于38%的患者会复发,因此需要进行长期随访。

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