Agrawal Ankit, Pabolu Sangeetha
Internal Medicine, Saint Peter's University Hospital - Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Rheumatology, Saint Peter's University Hospital - Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.
Cureus. 2019 May 16;11(5):e4680. doi: 10.7759/cureus.4680.
Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic inflammatory condition of the breast. Women of child-bearing age with a recent history of pregnancy and lactation are usually affected, and clinical picture mimics inflammatory breast cancer or breast abscess. The etiology is not well defined but proposed to be a localized immune reaction to the breast tissue. Here, we report a case of a 41-year-old female who presented with left breast pain and discharge and a clinical diagnosis of breast abscess was made. No improvement with antibiotics was noted and she underwent mammography and diagnostic ultrasound of the affected breast. A biopsy of the lesion was obtained which revealed chronic granulomatous inflammation confirming the diagnosis of IGM. She was also found to have hyperprolactinemia secondary to a prolactinoma following which the patient was started on steroid and bromocriptine.
特发性肉芽肿性乳腺炎（IGM）是一种罕见的、良性的乳腺慢性炎症性疾病。育龄期近期有妊娠和哺乳史的女性通常会受到影响，其临床表现类似炎性乳腺癌或乳腺脓肿。病因尚不明确，但推测是对乳腺组织的局部免疫反应。在此，我们报告一例41岁女性，她因左乳疼痛和溢液就诊，临床诊断为乳腺脓肿。使用抗生素治疗后未见改善，遂对患侧乳房进行了乳腺钼靶检查和诊断性超声检查。对病变进行活检，结果显示为慢性肉芽肿性炎症，确诊为IGM。还发现她因泌乳素瘤继发高泌乳素血症，随后患者开始接受类固醇和溴隐亭治疗。
