Billewicz Marta, Wojtania Joanna, Woźniacka Anna
Department of Dermatology and Venereology, Medical University of Lodz, Lodz, Poland.
Postepy Dermatol Alergol. 2024 Aug;41(4):350-356. doi: 10.5114/ada.2024.142185. Epub 2024 Aug 12.
Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterised by recurrent painful nodules, abscesses, fistulas and scarring. The primary distinguishing factor in the complex, yet still not fully understood, pathogenesis is an inflammation occurring within the hair follicle, followed by an immune response leading to further development of the skin lesions seen in HS. The treatment of patients with HS is very difficult due to the complexity of the lesions and the frequent tendency to recurrence, which also has a negative impact on the psychological state of patients and directly translates into a reduced quality of life. This review article addresses the pathogenesis, clinical presentation of HS and, in particular, explores the new therapeutic options available.
化脓性汗腺炎（HS）是一种慢性炎症性疾病，其特征为反复发作的疼痛性结节、脓肿、瘘管和瘢痕形成。在其复杂但仍未完全理解的发病机制中，主要的区别因素是毛囊内发生的炎症，随后引发免疫反应，导致HS中所见皮肤病变的进一步发展。由于病变的复杂性和频繁复发的倾向，HS患者的治疗非常困难，这也对患者的心理状态产生负面影响，并直接导致生活质量下降。这篇综述文章阐述了HS的发病机制、临床表现，尤其探讨了现有的新治疗选择。
