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化脓性汗腺炎:当前治疗选择综述

Hidradenitis suppurativa: a review of current treatment options.

作者信息

Lewandowski Miłosz, Świerczewska Zuzanna, Barańska-Rybak Wioletta

机构信息

Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.

出版信息

Int J Dermatol. 2022 Sep;61(9):1152-1164. doi: 10.1111/ijd.16115. Epub 2022 Feb 6.

DOI:10.1111/ijd.16115
PMID:35128643
Abstract

Hidradenitis suppurativa (HS) is a chronic, progressive, debilitating, recurrent inflammatory skin disease characterized by the occurrence of very severe, persistent, painful nodules, abscesses, and fistulas, most commonly found in the skin folds of the axilla, groin, gluteal, and perianal areas. The pathogenesis of HS is still not completely understood; currently, it is considered to be an immune-mediated inflammatory illness (IMID). Due to the significant decrease in the patients' quality of life and a delayed beginning of a treatment, the selection of the appropriate therapy is extremely important in these patients. Regardless of the fact that there are multiple treatment options for HS, no uniformly effective therapy has been found. All the guidelines underline the need for a multidisciplinary approach to the disease, which enables providers to create the right management of HS. This article aims to provide updates on the current treatment options of acne inversa to raise awareness and improve the management of the disease.

摘要

化脓性汗腺炎(HS)是一种慢性、进行性、使人衰弱的复发性炎症性皮肤病,其特征是出现非常严重、持续、疼痛的结节、脓肿和瘘管,最常见于腋窝、腹股沟、臀部和肛周区域的皮肤褶皱处。HS的发病机制仍未完全明确;目前,它被认为是一种免疫介导的炎症性疾病(IMID)。由于患者生活质量显著下降且治疗开始延迟,因此选择合适的治疗方法对这些患者极为重要。尽管HS有多种治疗选择,但尚未发现统一有效的疗法。所有指南都强调对该疾病需要采取多学科方法,这使医疗服务提供者能够对HS进行正确管理。本文旨在提供关于反向痤疮当前治疗选择的最新信息,以提高对该疾病的认识并改善其管理。

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