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[反向性痤疮]

[Acne inversa].

作者信息

Bechara F G, Hartschuh W

机构信息

Klinik für Dermatologie und Allergologie, Ruhr-Universität Bochum, Bochum, Deutschland.

出版信息

Hautarzt. 2010 Jan;61(1):39-46. doi: 10.1007/s00105-009-1813-2.

DOI:10.1007/s00105-009-1813-2
PMID:20012929
Abstract

Acne inversa is a chronic inflammatory disease of the hair follicles. It can lead to severe functional and psychological impairment. It is characterized by inflamed painful nodules, abscesses, fistulas and scarring in late stages of the disease. The causes of acne inversa are still not fully understood. Conservative treatment options such as antibiotics may lead to clinical improvement; however they do not produce healing. Therapy of choice, especially in severe forms, is radical wide excision of all affected areas. Despite a variety of treatment options, acne inversa is still a therapeutic challenge.

摘要

反向性痤疮是一种毛囊的慢性炎症性疾病。它可导致严重的功能和心理损害。其特征为在疾病后期出现发炎的疼痛性结节、脓肿、瘘管和瘢痕形成。反向性痤疮的病因仍未完全明确。抗生素等保守治疗方案可能会带来临床改善,但无法实现治愈。尤其是对于严重形式的反向性痤疮,首选的治疗方法是对所有受累区域进行广泛的根治性切除。尽管有多种治疗选择,但反向性痤疮仍然是一个治疗难题。

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引用本文的文献

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2
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Hautarzt. 2013 Jan;64(1):55-61; quiz 62. doi: 10.1007/s00105-012-2479-8.
3
Acne inversa: evaluating antimicrobial peptides and proteins.反向性痤疮:评估抗菌肽和蛋白质

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The effect of combined treatment with oral clindamycin and oral rifampicin in patients with hidradenitis suppurativa.口服克林霉素与口服利福平联合治疗对化脓性汗腺炎患者的疗效。
Dermatology. 2009;219(2):143-7. doi: 10.1159/000228337. Epub 2009 Jul 8.
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Combination therapy with clindamycin and rifampicin for hidradenitis suppurativa: a series of 116 consecutive patients.克林霉素与利福平联合治疗化脓性汗腺炎:116例连续病例系列
Dermatology. 2009;219(2):148-54. doi: 10.1159/000228334. Epub 2009 Jul 8.
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Long-term successful adalimumab therapy in severe hidradenitis suppurativa.
Ann Dermatol. 2012 Nov;24(4):393-7. doi: 10.5021/ad.2012.24.4.393. Epub 2012 Nov 8.
阿达木单抗治疗重度化脓性汗腺炎的长期成功案例
Arch Dermatol. 2009 May;145(5):580-4. doi: 10.1001/archdermatol.2009.49.
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Randomized control trial for the treatment of hidradenitis suppurativa with a neodymium-doped yttrium aluminium garnet laser.钕掺杂钇铝石榴石激光治疗化脓性汗腺炎的随机对照试验
Dermatol Surg. 2009 Aug;35(8):1188-98. doi: 10.1111/j.1524-4725.2009.01214.x. Epub 2009 May 12.
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Hidradenitis suppurativa: a comprehensive review.化脓性汗腺炎:一项全面综述。
J Am Acad Dermatol. 2009 Apr;60(4):539-61; quiz 562-3. doi: 10.1016/j.jaad.2008.11.911.
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Absence of efficacy of oral isotretinoin in hidradenitis suppurativa: a retrospective study based on patients' outcome assessment.口服异维A酸治疗化脓性汗腺炎无效:一项基于患者结局评估的回顾性研究
Dermatology. 2009;218(2):134-5. doi: 10.1159/000182261. Epub 2008 Dec 5.
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Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies.化脓性汗腺炎的患病率及相关因素:两项病例对照研究的结果
J Am Acad Dermatol. 2008 Oct;59(4):596-601. doi: 10.1016/j.jaad.2008.06.020.
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Hidradenitis suppurativa: are tumour necrosis factor-alpha blockers the ultimate alternative?化脓性汗腺炎:肿瘤坏死因子-α阻滞剂是最终的选择吗?
Br J Dermatol. 2008 Sep;159(3):761-3. doi: 10.1111/j.1365-2133.2008.08735.x. Epub 2008 Jul 9.
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What causes hidradenitis suppurativa?化脓性汗腺炎的病因是什么?
Exp Dermatol. 2008 May;17(5):455-6; discussion 457-72. doi: 10.1111/j.1600-0625.2008.00712_1.x.
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Long-term efficacy of etanercept in hidradenitis suppurativa.依那西普治疗化脓性汗腺炎的长期疗效。
J Eur Acad Dermatol Venereol. 2008 Nov;22(10):1260-2. doi: 10.1111/j.1468-3083.2008.02617.x. Epub 2008 Mar 7.