Department of Pediatrics, Division of Pulmonology, Allergy & Immunology, University of Tennessee Health Science Center, LeBonheur Children's Hospital, 51 N. Dunlap Street, Suite 400, Memphis, TN, 38105, USA.
Curr Allergy Asthma Rep. 2024 Nov;24(11):631-638. doi: 10.1007/s11882-024-01176-4. Epub 2024 Sep 19.
Exercise induced anaphylaxis (EIA) can be difficult to diagnose due to the interplay of co-factors on clinical presentation and the lack of standardized, confirmatory testing.
EIA has been historically categorized as either food-independent or food-dependent. However, recent literature has suggested that perhaps EIA is more complex given the relationship between not only food on EIA but other various co-factors such as medications and alcohol ingestion that are either required to elicit symptoms in EIA or make symptoms worse. For the practicing clinician, understanding how these co-factors can be implicated in EIA can enable one to take a more personalized approach in treating patients with EIA and thus improve quality of life for patients.
运动诱发的过敏反应(EIA)由于临床表现中共同因素的相互作用以及缺乏标准化的确认性检测,因此难以诊断。
EIA 过去被分为食物独立性或食物依赖性。然而,最近的文献表明,鉴于不仅是 EIA 中的食物,还包括其他各种共同因素(如药物和酒精摄入)与 EIA 症状的关系,EIA 可能更为复杂,这些因素要么是引发 EIA 症状的必要条件,要么使症状恶化。对于临床医生来说,了解这些共同因素如何与 EIA 相关联,可以使他们对 EIA 患者采用更个性化的治疗方法,从而提高患者的生活质量。