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DcR3 suppresses the NF-κB pathway and the NLRP3 inflammasome activation in gouty inflammation.

作者信息

Jiang Yi, Tu Xin, Guo Jianwei, Zheng Jianxiong, Liao Xia, He Yixi, Xie Yan, Zhang Quanbo, Qing Yufeng

机构信息

Research Center of Hyperuricemia and Gout, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.

Department of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.

出版信息

Chin Med J (Engl). 2024 Nov 5;137(21):2644-2646. doi: 10.1097/CM9.0000000000003274. Epub 2024 Sep 19.

DOI:10.1097/CM9.0000000000003274
PMID:39294866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11557038/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cf/11557038/ded5a79a4c8d/cm9-137-2644-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cf/11557038/ded5a79a4c8d/cm9-137-2644-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3cf/11557038/ded5a79a4c8d/cm9-137-2644-g001.jpg

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本文引用的文献

1
Gout: a disease involved with complicated immunoinflammatory responses: a narrative review.痛风：一种涉及复杂免疫炎症反应的疾病：一篇叙述性综述
Clin Rheumatol. 2020 Oct;39(10):2849-2859. doi: 10.1007/s10067-020-05090-8. Epub 2020 May 7.
2
NF-κB signaling in inflammation.NF-κB 信号转导与炎症
Signal Transduct Target Ther. 2017;2:17023-. doi: 10.1038/sigtrans.2017.23. Epub 2017 Jul 14.
3
Inflammation in gout: mechanisms and therapeutic targets.痛风中的炎症：机制和治疗靶点。
Nat Rev Rheumatol. 2017 Nov;13(11):639-647. doi: 10.1038/nrrheum.2017.155. Epub 2017 Sep 28.
4
Decoy receptor 3: an endogenous immunomodulator in cancer growth and inflammatory reactions.诱饵受体3：癌症生长和炎症反应中的内源性免疫调节剂
J Biomed Sci. 2017 Jun 19;24(1):39. doi: 10.1186/s12929-017-0347-7.
5
The TL1A/DR3/DcR3 pathway in autoimmune rheumatic diseases.TL1A/DR3/DcR3 通路在自身免疫性风湿病中的作用。
Semin Arthritis Rheum. 2015 Aug;45(1):1-8. doi: 10.1016/j.semarthrit.2015.02.007. Epub 2015 Feb 20.
6
Role of TL1A in the pathogenesis of rheumatoid arthritis.TL1A在类风湿关节炎发病机制中的作用。
J Immunol. 2009 Oct 15;183(8):5350-7. doi: 10.4049/jimmunol.0802645. Epub 2009 Sep 28.
7
Gout-associated uric acid crystals activate the NALP3 inflammasome.痛风相关的尿酸晶体激活NALP3炎性小体。
Nature. 2006 Mar 9;440(7081):237-41. doi: 10.1038/nature04516. Epub 2006 Jan 11.
8
TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells.肿瘤坏死因子样配体1A（TL1A）诱导的核因子κB（NF-κB）激活和细胞凋亡抑制蛋白2（c-IAP2）生成可防止DR3介导的TF-1细胞凋亡。
J Biol Chem. 2003 Oct 3;278(40):39251-8. doi: 10.1074/jbc.M305833200. Epub 2003 Jul 25.