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2
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本文引用的文献

1
Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary.全球慢性阻塞性肺疾病倡议 2023 年报告：GOLD 执行摘要。
Eur Respir J. 2023 Apr 1;61(4). doi: 10.1183/13993003.00239-2023. Print 2023 Apr.
2
Endoscopic Valve Therapy in COPD Patients with Hypercapnia.内镜下瓣治疗合并高碳酸血症的 COPD 患者。
Respiration. 2022;101(10):918-924. doi: 10.1159/000525729. Epub 2022 Aug 23.
3
Survival in COPD patients treated with bronchoscopic lung volume reduction.接受支气管镜肺减容治疗的慢性阻塞性肺疾病患者的生存率。
Respir Med. 2022 May;196:106825. doi: 10.1016/j.rmed.2022.106825. Epub 2022 Mar 16.
4
Effect of average volume-assured pressure support treatment on health-related quality of life in COPD patients with chronic hypercapnic respiratory failure: a randomized trial.平均容量保证压力支持治疗对慢性高碳酸血症呼吸衰竭 COPD 患者健康相关生活质量的影响：一项随机试验。
Respir Res. 2020 Mar 6;21(1):64. doi: 10.1186/s12931-020-1320-7.
5
A Multicenter Randomized Controlled Trial of Zephyr Endobronchial Valve Treatment in Heterogeneous Emphysema (LIBERATE).Zephyr 支气管内阀治疗异质性肺气肿的多中心随机对照试验（LIBERATE）。
Am J Respir Crit Care Med. 2018 Nov 1;198(9):1151-1164. doi: 10.1164/rccm.201803-0590OC.
6
A Multicenter Randomized Controlled Trial of Zephyr Endobronchial Valve Treatment in Heterogeneous Emphysema (TRANSFORM).Zephyr 支气管内活瓣治疗不均质肺气肿的多中心随机对照试验（TRANSFORM）。
Am J Respir Crit Care Med. 2017 Dec 15;196(12):1535-1543. doi: 10.1164/rccm.201707-1327OC.
7
Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial.无创正压通气治疗严重稳定期慢性阻塞性肺疾病前瞻性多中心随机对照临床研究
Lancet Respir Med. 2014 Sep;2(9):698-705. doi: 10.1016/S2213-2600(14)70153-5. Epub 2014 Jul 24.
8
Randomized trial of 'intelligent' autotitrating ventilation versus standard pressure support non-invasive ventilation: impact on adherence and physiological outcomes.随机试验比较“智能”自动滴定通气与标准压力支持无创通气：对依从性和生理结果的影响。
Respirology. 2014 May;19(4):596-603. doi: 10.1111/resp.12269. Epub 2014 Mar 24.
9
Respiratory failure in chronic obstructive pulmonary disease.慢性阻塞性肺疾病中的呼吸衰竭
Eur Respir J Suppl. 2003 Nov;47:26s-30s. doi: 10.1183/09031936.03.00030103.

高碳酸血症作为支气管镜下肺减容术的绝对排除标准。

Hypercapnia as an absolute exclusion criteria for bronchoscopic lung volume reduction.

作者信息

Burgei Jonathan W, Alsheimer Katie, Lantry Julia, Swalih Mohamed, Hehn Boyd

机构信息

Robert Packer Hospital, Guthrie Clinic, Pulmonary, Critical Care Department, USA.

出版信息

Respir Med Case Rep. 2024 Aug 28;51:102100. doi: 10.1016/j.rmcr.2024.102100. eCollection 2024.

DOI:10.1016/j.rmcr.2024.102100
PMID:39295634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11408847/
Abstract

Bronchoscopic lung volume reduction is a procedure that involves placement of valves into the lung to intentionally cause atelectasis to help with perfusion-ventilation matching. There are strict exclusion criteria, such as hypercapnia, that prevent patients from qualifying for the procedure based on the early trials. We present a case of a patient that became a candidate for the procedure after utilizing AVAPS after BPAP failed to lower his PCO2 to qualify for the procedure. Additionally, newer studies show that patients who are hypercapnic might benefit from the procedure to improve hypercapnia.

摘要

支气管镜肺减容术是一种将瓣膜置入肺部以故意造成肺不张，从而帮助改善通气灌注匹配的手术。该手术存在严格的排除标准，如高碳酸血症，这使得基于早期试验结果，患者不符合手术条件。我们报告了一例患者，在双水平气道正压通气（BPAP）未能降低其二氧化碳分压（PCO₂）以符合手术条件后，使用自适应通气辅助压力支持（AVAPS）后该患者成为了该手术的候选对象。此外，最新研究表明，高碳酸血症患者可能从该手术中获益，以改善高碳酸血症。